Evidence map›Paper›PMID 28812400›Full record

ArticleScandinavian journal of primary health care2017

New benzodiazepine and Z-hypnotic users and disability pension: an eight-year nationwide observational follow-up study.

Ingunn F Tvete, Trine Bjørner, Tor Skomedal

Open access · goldAbstract readComparative Study
In one paragraph

Article in Scandinavian journal of primary health care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Long-term benzodiazepine use and risk of labor market marginalization in Finland: A cohort study with 5-year follow-up.European psychiatry : the journal of the Association of European Psychiatrists · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ingunn F Tvetea The Norwegian Computing Center , Oslo , Norway.
Trine Bjørnerb Department of General Practice , Institute of Health and Society, University of Oslo , Oslo , Norway.
Tor Skomedalc Department of Pharmacology , Institute of Clinical Medicine, University of Oslo , Oslo , Norway.
University of Oslo · NONorwegian Computing Center · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare how newly initiated treatment with benzodiazepines, Z-hypnotics or both associates with the reception of disability pension among 40,661 individuals of a working age.

designPrescription register study.

settingNorwegian nationwide prescriptions socio-economic and disability status data.

methodsCox regression analyses. SUBJECTS: New benzodiazepine or Z-hypnotic users.

main outcome measureTime to receive disability pension given benzodiazepine or Z-hypnotic use or both. Additional analyses focused on the benzodiazepine first redeemed.

resultsAmong new users 8.65% of Z-hypnotic users, 12.29% of benzodiazepines users and 13.96% of combined Z-hypnotic and benzodiazepine users became disability pensioners. Z-hypnotic users were weaker associated with becoming disability pensioners (HR = 0.78, CI: 0.73-0.84) and combined users were stronger associated (HR = 1.09, CI: 1.01-1.17), than benzodiazepine users. Women had higher risk than men for becoming disability pensioners. Higher age, lower education, previous drug use and psychiatrist as first prescriber were risk factors. Comparing first benzodiazepine redeemed; clonazepam initiators were stronger associated with becoming disability pensioners than diazepam initiators were (HR = 2.22, CI: 1.81-2.71). No differences between other benzodiazepine users were found.

conclusionsAdjusting for known risk factors gave lower risk for Z-hypnotic users compared to benzodiazepine users for receiving disability pension. Combined use increased the risk further. Clonazepam initiators are especially at risk. These findings may be helpful in prescribing situations to identify and guide individuals at risk for becoming disability pensioners.

Indexed as

BenzodiazepinesDrug PrescriptionsHypnotics and SedativesPensionsPersons with DisabilitiesAdultClonazepamDiazepamFemaleFollow-Up StudiesHumansMaleMiddle AgedNorwayRegression AnalysisRisk FactorsBenzodiazepinesClonazepamDiazepamHypnotics and SedativesBenzodiazepinescox regressiondisability pensionmental disordersorescription register datawork lifeZ-hypnotica

Identifiers

PMID28812400
PMCPMC5592350
OpenAlexW2748084792

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.