Evidence map›Paper›PMID 28812256›Full record

ReviewCurrent allergy and asthma reports2017

The Potential for Emerging Microbiome-Mediated Therapeutics in Asthma.

Ayse Bilge Ozturk, Benjamin Arthur Turturice, David L Perkins, Patricia W Finn

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Novel potential treatable traits in asthma: Where is the research taking us?The journal of allergy and clinical immunology. Global · 2022
    Review
  5. Review
  6. Article
  7. The current state of omics technologies in the clinical management of asthma and allergic diseases.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2019
    Review
  8. The Role of the Microbiome in Asthma: The Gut⁻Lung Axis.International journal of molecular sciences · 2018
    Review
  9. Review
  10. Microbiome and asthma.Asthma research and practice · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ayse Bilge OzturkDepartment of Allergy and Immunology, Koc University Hospital, Istanbul, Turkey.
Benjamin Arthur TurturiceDepartment of Microbiology and Immunology, University of Illinois at Chicago, Chicago, IL, USA.
David L PerkinsDepartment of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Patricia W FinnDepartment of Microbiology and Immunology, University of Illinois at Chicago, Chicago, IL, USA. pwfinn@uic.edu.
University of Illinois Chicago · USKoç University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewIn terms of immune regulating functions, analysis of the microbiome has led the development of therapeutic strategies that may be applicable to asthma management. This review summarizes the current literature on the gut and lung microbiota in asthma pathogenesis with a focus on the roles of innate molecules and new microbiome-mediated therapeutics. RECENT

findingsRecent clinical and basic studies to date have identified several possible therapeutics that can target innate immunity and the microbiota in asthma. Some of these drugs have shown beneficial effects in the treatment of certain asthma phenotypes and for protection against asthma during early life. Current clinical evidence does not support the use of these therapies for effective treatment of asthma. The integration of the data regarding microbiota with technologic advances, such as next generation sequencing and omics offers promise. Combining comprehensive bioinformatics, new molecules and approaches may shape future asthma treatment.

Indexed as

Immunity, InnateAnimalsAsthmaGastrointestinal MicrobiomeGastrointestinal TractHigh-Throughput Nucleotide SequencingHumansInterleukin-33LungPhenotypeInterleukin-33AsthmaInnate immunityInterleukin-33MicrobiotaThymic stromal lymphopoietinToll-like receptors

Identifiers

PMID28812256
OpenAlexW2744085101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.