Evidence map›Paper›PMID 28812237›Full record

ArticleJournal of molecular neuroscience : MN2017

Pharmacological Effects on Ceroid Lipofuscin and Neuronal Structure in Cln3

Douglas E Brenneman, David A Pearce, Attila Kovacs, Shawn DeFrees

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Activation of PPARα Exhibits Therapeutic Efficacy in a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Douglas E BrennemanAdvanced Neural Dynamics, Inc., Pennsylvania Biotechnology Center, 3805 Old Easton Road, Doylestown, PA, 18902, USA. brenne3@verizon.net.
David A PearceSanford Children's Health Research Center, Sanford Research, Sioux Falls, SD, 57104, USA.
Attila KovacsSanford Children's Health Research Center, Sanford Research, Sioux Falls, SD, 57104, USA.
Shawn DeFreesSeneb Bioscience, Inc., Pennsylvania Biotechnology Center, 3805 Old Easton Road, Doylestown, PA, 18902, USA.
Sanford Research · USAdvanced Neural Dynamics (United States) · USSeneb BioSciences (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Juvenile Batten disease (JBD) is an inherited disorder that is characterized by the development of blindness, seizures, and progressive motor, psychiatric, and cognitive impairment. A model of JBD expressing the predominant human mutation (Cln3

Indexed as

AminopeptidasesAnimalsATP Synthetase ComplexesBrainCells, CulturedCytoplasmic GranulesDipeptidyl-Peptidases and Tripeptidyl-PeptidasesGalactosylceramidesLipofuscinMembrane GlycoproteinsMiceMolecular ChaperonesNeuronal Ceroid-LipofuscinosesNeuronsSerine ProteasesTripeptidyl-Peptidase 1AminopeptidasesATP Synthetase ComplexesCLN3 protein, mouseDipeptidyl-Peptidases and Tripeptidyl-PeptidasesGalactosylceramidesLipofuscinMembrane GlycoproteinsMolecular ChaperonesSerine ProteasesTripeptidyl-Peptidase 1Ceroid lipofuscinCln3 ∆ex7/8High content analysisJuvenile Batten diseaseMitochondrial ATP synthase subunit cβ-galactosyl ceramide

Identifiers

PMID28812237
OpenAlexW2749880279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.