Evidence map›Paper›PMID 28812231›Full record

ArticleMolecular neurobiology2018

The Neuroprotective Effect of Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cells is Impaired by N-acetyl Cysteine Supplementation.

Teodoro Palomares, María Cordero, Cristina Bruzos-Cidon, María Torrecilla, Luisa Ugedo, Ana Alonso-Varona

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

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  4. Conditioned Medium from HAntioxidants (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Teodoro PalomaresDepartment of Surgery and Radiology and Physical Medicine, University of the Basque Country (UPV/EHU), Leioa, Bizkaia, Spain. teodoro.palomares@ehu.eus.
María CorderoDepartments of Cell Biology and Histology, University of the Basque Country (UPV/EHU), Leioa, Bizkaia, Spain.
Cristina Bruzos-CidonDepartment of Pharmacology, University of the Basque Country (UPV/EHU), Leioa, Bizkaia, Spain.
María TorrecillaDepartment of Pharmacology, University of the Basque Country (UPV/EHU), Leioa, Bizkaia, Spain.
Luisa UgedoDepartment of Pharmacology, University of the Basque Country (UPV/EHU), Leioa, Bizkaia, Spain.
Ana Alonso-VaronaDepartments of Cell Biology and Histology, University of the Basque Country (UPV/EHU), Leioa, Bizkaia, Spain.
University of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress is a common feature in neurodegenerative diseases associated with neuroinflammation, and therefore, has been proposed as a key target for novel therapies for these diseases. Recently, adipose-derived stem cell (ASC)-based cell therapy has emerged as a novel strategy for neuroprotection. In this study, we evaluate the therapeutic role of ASC-conditioned medium (ASC-CM) against H

Indexed as

AcetylcysteineAdipocytesCell DifferentiationCell Line, TumorCells, CulturedCell SurvivalCoculture TechniquesCulture Media, ConditionedHumansMesenchymal Stem CellsNeuroprotective AgentsOxidative StressReactive Oxygen SpeciesAcetylcysteineCulture Media, ConditionedNeuroprotective AgentsReactive Oxygen SpeciesAdipose-derived stem cellsConditioned mediumN-acetyl cysteineNeurodegenerative diseasesOxidative stressSH-SY5Y cells

Identifiers

PMID28812231
OpenAlexW2750261640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.