Evidence map›Paper›PMID 28812061›Full record

ArticleeNeuro

Behavioral Comorbidities and Drug Treatments in a Zebrafish

Brian P Grone, Tiange Qu, Scott C Baraban

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Nontraditional Antiseizure Medications to Consider When Traditional Options Have Failed: Medications for Refractory Seizures and Epilepsies.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Use of Zebrafish Models to Boost Research in Rare Genetic Diseases.International journal of molecular sciences · 2021
    Review
  18. Mutants of the Zebrafish KInternational journal of molecular sciences · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brian P GroneEpilepsy Research Laboratory in the Department of Neurological Surgery, University of California, San Francisco, CA.ORCID 0000-0003-3737-2724
Tiange QuEpilepsy Research Laboratory in the Department of Neurological Surgery, University of California, San Francisco, CA.ORCID 0000-0001-5132-4484
Scott C BarabanEpilepsy Research Laboratory in the Department of Neurological Surgery, University of California, San Francisco, CA.ORCID 0000-0003-1975-9781
University of California, San Francisco · US

Funding

ZEBRAFISH MODELS FOR DRAVET SYNDROME RESEARCH AND DISCOVERYR01NS096976 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BARABAN, SCOTT C · 2016 to 2024
$3.9M
Using Zebrafish to Advance our Understanding and Treatment of EpilepsyR01NS079214 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BARABAN, SCOTT C · 2012 to 2015
$1.2M
NINDS NIH HHS R01 NS079214NINDS NIH HHS R01 NS096976
6 · The paper itself

Abstract

Loss-of-function mutations in

Indexed as

Epilepsies, MyoclonicAnimalsAnimals, Genetically ModifiedAnticonvulsantsCell CountCircadian RhythmCognitive Behavioral TherapyDisease Models, AnimalExploratory BehaviorFemaleGenotypeGreen Fluorescent ProteinsInterneuronsLarvaLocomotionMaleAnticonvulsantsGreen Fluorescent ProteinsNAV1.1 Voltage-Gated Sodium ChannelZebrafish ProteinsanxietyDravet syndromeepilepsysleepsodium channelszebrafish

Identifiers

PMID28812061
PMCPMC5555352
OpenAlexW2743519346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.