ArticleJournal of nutrition and metabolism2017
Association between Salivary Leptin Levels and Taste Perception in Children.
Article in Journal of nutrition and metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- High physical activity is associated with decreased fungiform papillae area and number, elevated sucrose recognition thresholds, and increased IL-6 levels: an observational human study.Nutrition & metabolism · 2025Article
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- Covid-19: Signs and symptoms related to the feeding behavior.Physiology & behavior · 2021Article
- Evaluation of Salivary Leptin Levels and Its Correlation with Class I, Class II, and Class III Facial Skeletal Pattern: A Prefatory Study.European journal of dentistry · 2021Article
- Phosphatidylinositol-3 kinase mediates the sweet suppressive effect of leptin in mouse taste cells.Journal of neurochemistry · 2021Article
- Salivary Protein Profile and Food Intake: A Dietary Pattern Analysis.Journal of nutrition and metabolism · 2021Article
- Consequences of Obesity on the Sense of Taste: Taste Buds as Treatment Targets?Diabetes & metabolism journal · 2020Review
- Comparison of salivary proteome of children with different sensitivities for bitter and sweet tastes: association with body mass index.International journal of obesity (2005) · 2019Article
- A Randomized Placebo-controlled Trial of an Oral Preparation of High Molecular Weight Fucoidan in Patients with Type 2 Diabetes with Evaluation of Taste Sensitivity.Yonago acta medica · 2019Article
- A Review of Selected Studies That Determine the Physical and Chemical Properties of Saliva in the Field of Dental Treatment.BioMed research international · 2018Review
- The Interplay of Salivary Leptin, Taste Perception, and Dental Caries in Adolescent Girls: A Cross-Sectional Analysis Across Body Mass Index Categories.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The satiety inducing hormone leptin acts not only at central nervous system but also at peripheral level. Leptin receptors are found in several sense related organs, including the mouth. A role of leptin in sweet taste response has been suggested but, until now, studies have been based on in vitro experiments, or in assessing the levels of the hormone in circulation. The present study investigated whether the levels of leptin in saliva are related to taste perception in children and whether Body Mass Index (BMI) affects such relationship. Sweet and bitter taste sensitivity was assessed for 121 children aged 9-10 years and unstimulated whole saliva was collected for leptin quantification, using ELISA technique. Children females with lower sweet taste sensitivity presented higher salivary leptin levels, but this is only in the normal weight ones. For bitter taste, association between salivary leptin and caffeine threshold detection was observed only in preobese boys, with higher levels of salivary hormone in low sensitive individuals. This study is the first presenting evidences of a relationship between salivary leptin levels and taste perception, which is sex and BMI dependent. The mode of action of salivary leptin at taste receptor level should be elucidated in future studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.