ArticlePakistan journal of medical sciences
Differentiation of beta thalassemia trait from iron deficiency anemia by hematological indices.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 77 citations in OpenAlex.
- Systematic common and rare variant association testing in 392,030 whole genomes inmedRxiv : the preprint server for health sciences · 2026Article
- Assessment of β-Thalassemia Trait Occurrence in an Outpatient Sample from Southern Chile: A Retrospective Study.Diagnostics (Basel, Switzerland) · 2025Article
- Evaluation of β-thalassemias in the premarital hemoglobinopathy screening program: A retrospective study.Pakistan journal of medical sciences · 2025Article
- Digital Imaging of Peripheral Blood Smear With MC-80 as a Screening Tool for Thalassemia.Journal of clinical laboratory analysis · 2025Article
- High prevalence and molecular spectrum ofThe Egyptian journal of medical human genetics · 2025Article
- First-trimester nutrition insights from the United Arab Emirate Birth Cohort Study (UAE-BCS): assessment of dietary intake, micronutrient profiles, and folic acid supplementation in Emirati Women.Journal of nutritional science · 2025Article
- Diagnostic Performance of Red Blood Cell Indices in the Differential Diagnosis of Iron Deficiency Anemia and the Thalassemia Trait in Chile: A Retrospective Study.Diagnostics (Basel, Switzerland) · 2024Article
- Reference values for reticulocyte haemoglobin equivalent in healthy Chinese children under 5 years and its associations with various blood parameters.BMJ paediatrics open · 2024Article
- Article
- A New Formula Based on Simple Blood Indices to Differentiate Beta Thalassemia Trait from Iron Deficiency Anemia.Iranian journal of public health · 2024Article
- Dry eye in thalassemia.Indian journal of ophthalmology · 2023Article
- The Evaluation of Results of Twenty Common Equations for Differentiation of Beta Thalassemia Trait from Iron Deficiency Anemia: A Cross-Sectional Study.Iranian journal of public health · 2022Article
- Prevalence of iron deficiency anemia and beta thalassemia carriers among relatives of beta thalassemia patients in Nile Delta region, Egypt: a multicenter study.The Journal of the Egyptian Public Health Association · 2021Article
- Application of Bayesian Decision Tree in Hematology Research: Differential Diagnosis ofComputational and mathematical methods in medicine · 2021Article
- Anaemia Among Children Who Attended the Children's Teaching Hospital in Karbala, Iraq.Journal of blood medicine · 2021Article
- A Case of COVID-19 in a Patient with Asymptomatic Hemoglobin D Thalassemia and Glucose-6-Phosphate Dehydrogenase Deficiency.The American journal of case reports · 2020Article
- HV2 fragment mutations in β-thalassemia patients and a new base pair insertion of high-altitude cases.American journal of blood research · 2020Article
- Deletional Alpha-Thalassemia Alleles in Amazon Blood Donors.Advances in hematology · 2020Article
- Diagnostic performance of hematological discrimination indices to discriminate between βeta thalassemia trait and iron deficiency anemia and using cluster analysis: Introducing two new indices tested in Iranian population.Scientific reports · 2019Article
- Role of Mentzer index for differentiating iron deficiency anemia and beta thalassemia trait in pregnant women.Pakistan journal of medical sciencesArticle
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Authors and funding
5 authors at 4 institutions in 1 country.
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Abstract
objectiveWe aimed at finding out reliable parameter in the differentiation of iron deficiency anemia (IDA) and beta-thalassemia trait (β-TT) in the adult population subjected to Saudi Arabian Premarital Screening Program.
methodsA total of 620 adults (age range 21-36 years) reported during February 2012 to November 2012. Tests for serum iron and ferritin were carried out in individuals showing low hemoglobin (Hb). All the selected subjects' samples were subjected to blood morphology, comparison of MCV, RBC count. Red Cell Distribution Width (RDW) was noted from the Coulter Report whereas Red Cell Distribution Width Index (RDWI) value was calculated for all the samples.
resultsA total of one hundred &thirty-five individuals with hypochromic microcytic anemia having normal hemoglobin F and hemoglobin A2 < 3.2% were inducted in the study. Ninety-three were diagnosed having IDA, whereas thirty-two were having βTT. Ten individuals revealed other causes of anemia. The RBC count was higher, and MCV was much lower in βTT as compared to IDA. Both groups were subjected to RDW and RDWI, however, RDWI which showed better sensitivity and specificity for βTT.
conclusionRDWI is a reliable and useful index for differentiation among IDA and βTT, as compared to RDW.
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