Evidence map›Paper›PMID 28811713›Full record

ArticleWorld journal of gastroenterology2017

Clinical significance of glycemic parameters on venous thromboembolism risk prediction in gastrointestinal cancer.

Fiorella Guadagni, Silvia Riondino, Vincenzo Formica, Girolamo Del Monte, Anna Maria Morelli, Jessica Lucchetti, Antonella Spila, Roberta D'Alessandro, David Della-Morte, Patrizia Ferroni and 1 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Fiorella GuadagniFiorella Guadagni, David Della-Morte, Patrizia Ferroni, San Raffaele Roma Open University, 00166 Rome, Italy.
Silvia RiondinoFiorella Guadagni, David Della-Morte, Patrizia Ferroni, San Raffaele Roma Open University, 00166 Rome, Italy.
Vincenzo FormicaFiorella Guadagni, David Della-Morte, Patrizia Ferroni, San Raffaele Roma Open University, 00166 Rome, Italy.
Girolamo Del MonteFiorella Guadagni, David Della-Morte, Patrizia Ferroni, San Raffaele Roma Open University, 00166 Rome, Italy.
Anna Maria MorelliFiorella Guadagni, David Della-Morte, Patrizia Ferroni, San Raffaele Roma Open University, 00166 Rome, Italy.
Jessica LucchettiFiorella Guadagni, David Della-Morte, Patrizia Ferroni, San Raffaele Roma Open University, 00166 Rome, Italy.
Antonella SpilaFiorella Guadagni, David Della-Morte, Patrizia Ferroni, San Raffaele Roma Open University, 00166 Rome, Italy.
Roberta D'AlessandroFiorella Guadagni, David Della-Morte, Patrizia Ferroni, San Raffaele Roma Open University, 00166 Rome, Italy.
David Della-MorteFiorella Guadagni, David Della-Morte, Patrizia Ferroni, San Raffaele Roma Open University, 00166 Rome, Italy.
Patrizia FerroniFiorella Guadagni, David Della-Morte, Patrizia Ferroni, San Raffaele Roma Open University, 00166 Rome, Italy.
Mario RoselliFiorella Guadagni, David Della-Morte, Patrizia Ferroni, San Raffaele Roma Open University, 00166 Rome, Italy.
San Raffaele University of Rome · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto di Ricovero e Cura a Carattere Scientifico San RaffaeleUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the possible predictive role of routinely used glycemic parameters for a first venous thromboembolism (VTE) episode in gastrointestinal (GI) cancer ambulatory patients - with or without clinically diagnosed type 2 diabetes (T2D) or obesity - treated with chemotherapy.

methodsPre-treatment fasting blood glucose, insulin, glycated hemoglobin (HbA

resultsImpaired glucose tolerance (IGT) or T2D were diagnosed in 30% of GI cancer patients, while overweight/obesity had an incidence of 41%. VTE occurred in 9.4% of patients (7% of non-diabetic non-obese), especially in those with a high ECOG score (

conclusionThe results here reported demonstrate that evaluating glucose metabolic asset may allow for VTE risk stratification in GI cancer, helping to identify chemotherapy-treated patients who might benefit from thromboprophylaxis. Further multicenter prospective studies involving a larger number of patients are presently needed.

Indexed as

AdultAgedAged, 80 and overAnticoagulantsAntineoplastic AgentsBevacizumabBiomarkersBlood GlucoseChemotherapy, AdjuvantDiabetes Mellitus, Type 2FemaleGastrointestinal NeoplasmsGlucoseGlucose IntoleranceGlycated HemoglobinHumansAnticoagulantsAntineoplastic AgentsBevacizumabBiomarkersBlood GlucoseGlucoseGlycated HemoglobinInsulinChemotherapyGastrointestinal cancerInsulin resistanceType 2 diabetesVenous thromboembolism

Identifiers

PMID28811713
PMCPMC5537185
OpenAlexW2739916755

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.