Evidence map›Paper›PMID 28811712›Full record

ArticleWorld journal of gastroenterology2017

Association between

Xue-Qi Chen, Jia-Yu Mao, Wen-Bin Li, Jian Li, Hong Yang, Jia-Ming Qian, Jing-Nan Li

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xue-Qi ChenXue-Qi Chen, Jia-Yu Mao, Wen-Bin Li, Hong Yang, Jia-Ming Qian, Jing-Nan Li, Department of Gastroenterology, Peking Union Medical College Hospital, Beijing 100730, China.
Jia-Yu MaoXue-Qi Chen, Jia-Yu Mao, Wen-Bin Li, Hong Yang, Jia-Ming Qian, Jing-Nan Li, Department of Gastroenterology, Peking Union Medical College Hospital, Beijing 100730, China.
Wen-Bin LiXue-Qi Chen, Jia-Yu Mao, Wen-Bin Li, Hong Yang, Jia-Ming Qian, Jing-Nan Li, Department of Gastroenterology, Peking Union Medical College Hospital, Beijing 100730, China.
Jian LiXue-Qi Chen, Jia-Yu Mao, Wen-Bin Li, Hong Yang, Jia-Ming Qian, Jing-Nan Li, Department of Gastroenterology, Peking Union Medical College Hospital, Beijing 100730, China.
Hong YangXue-Qi Chen, Jia-Yu Mao, Wen-Bin Li, Hong Yang, Jia-Ming Qian, Jing-Nan Li, Department of Gastroenterology, Peking Union Medical College Hospital, Beijing 100730, China.
Jia-Ming QianXue-Qi Chen, Jia-Yu Mao, Wen-Bin Li, Hong Yang, Jia-Ming Qian, Jing-Nan Li, Department of Gastroenterology, Peking Union Medical College Hospital, Beijing 100730, China.
Jing-Nan LiXue-Qi Chen, Jia-Yu Mao, Wen-Bin Li, Hong Yang, Jia-Ming Qian, Jing-Nan Li, Department of Gastroenterology, Peking Union Medical College Hospital, Beijing 100730, China.
Henan Cancer Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNPeking Union Medical College Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the pathogenesis and potential single nucleotide polymorphisms (SNPs) as screening sites for colonic polyps, colon cancer and ulcerative colitis, and to analyze the possible association between these genetic polymorphisms and the three diseases.

methodsWe evaluated genetic polymorphisms in 144 newly diagnosed colonic polyp patients, 96 colon cancer patients and 44 ulcerative colitis patients. The four SNPs genotyped were rs4809957, rs6068816, rs6091822 and rs8124792. The control group consisted of 504 East Asians enrolled in the 1000 Genomes Project. Correlations between

results

conclusionFour SNPs are related to the risk of colonic polyps and colon cancer. G allele in rs6091822 G/T may play an anti-cancer role only if it is homozygous. The A allele, which is a minor component of rs8124792, may be indicated in the diagnosis of colonic polyps or colon cancer rather than ulcerative colitis.

Indexed as

AdultAgedAsian PeopleBiomarkers, TumorCase-Control StudiesColitis, UlcerativeColonic NeoplasmsColonic PolypsEarly Detection of CancerFemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHumansMaleMass ScreeningBiomarkers, TumorCYP24A1 protein, humanVitamin D3 24-HydroxylaseColon cancerColonic polypsCYP24A1Single nucleotide polymorphisms

Identifiers

PMID28811712
PMCPMC5537184
OpenAlexW2740706921

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.