ArticleScientific reports2017
Assessment of the role of ageing and non-ageing factors in death from non-communicable diseases based on a cumulative frequency model.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
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- Desired weight loss and its association with health, health behaviors and perceptions in an adult population with weight excess: One-year follow-up.Frontiers in nutrition · 2022Article
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- A grading system from health to death using routine experimental indicators based on the pre-chronic disease status theory.BMC geriatrics · 2020Article
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- Two Time Point Analysis of the Change in Risk and Aging Factors for Major Cancers: A 10-Year Longitudinal Study in China.BioMed research international · 2020Article
- Heredity Indexes for Estimating Heritability Using Known and Unknown Family Data Based on the Model of Polygenic Inheritance.Computational and mathematical methods in medicine · 2020Article
- Comprehensive analysis of circular RNAs in pathological states: biogenesis, cellular regulation, and therapeutic relevance.Cellular and molecular life sciences : CMLS · 2019Review
- Quantifying the effects of aging and urbanization on major gastrointestinal diseases to guide preventative strategies.BMC gastroenterology · 2018Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To quantify the effects of ageing and non-ageing factors, a characterization of the effects of ageing, genetic, and exogenous variables on 12 major non-communicable diseases was evaluated using a model assessing cumulative frequency of death and survival by age group from dead and surviving populations based on mortality statistics. Indices (0-1) of the roles of ageing (ARD), genetics (GRD) and exogenous (ERD) variables in deaths due to disease were established, and the sum of ARD, GRD and ERD was 1 (value of each indices was <1). Results showed that ageing plays an important role in death from chronic disease; exogenous factors may contribute more to the pattern of chronic disease than genetic factors (ARD, GRC and ERD were 0.818, 0.058 and 0.124 respectively for all non-communicable diseases). In descending order, ERD for non-communicable diseases were breast cancer, leukaemia, cancer of the cervix uteri and uterus, liver cancer, nephritis and nephropathy, stomach cancer, lung cancer, diabetes, cerebrovascular disease, coronary heart disease, COPD, and Alzheimer's disease, while a smaller ERD indicated a tendency of natural death. An understanding of the aforementioned complex relationships of specific non-communicable diseases will be beneficial in designing primary prevention measures for non-communicable diseases in China.
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