ArticleScientific reports2017
Sealing the Pores of PEO Coating with Mg-Al Layered Double Hydroxide: Enhanced Corrosion Resistance, Cytocompatibility and Drug Delivery Ability.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Advanced Strategies for Enhancing the Biocompatibility and Antibacterial Properties of Implantable Structures.Materials (Basel, Switzerland) · 2025Review
- Review
- Advances in amelioration of plasma electrolytic oxidation coatings on biodegradable magnesium and alloys.Heliyon · 2024Review
- Layered Double Hydroxides: A Novel Promising 2D Nanomaterial for Bone Diseases Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- Synthesis of Zeolitic imidazolate frameworks-8@ layered double hydroxide polyhedral nanocomposite with designed porous voids as an effective carrier for anti-cancer drug-controlled delivery.IET nanobiotechnology · 2023Article
- Chromate-Free Corrosion Protection Strategies for Magnesium Alloys-A Review: PART I-Pre-Treatment and Conversion Coating.Materials (Basel, Switzerland) · 2022Review
- Advances in the development of biodegradable coronary stents: A translational perspective.Materials today. Bio · 2022Review
- Chromate-Free Corrosion Protection Strategies for Magnesium Alloys-A Review: Part II-PEO and Anodizing.Materials (Basel, Switzerland) · 2022Review
- Chromate-Free Corrosion Protection Strategies for Magnesium Alloys-A Review: Part III-Corrosion Inhibitors and Combining Them with Other Protection Strategies.Materials (Basel, Switzerland) · 2022Review
- Black Mn-containing layered double hydroxide coated magnesium alloy for osteosarcoma therapy, bacteria killing, and bone regeneration.Bioactive materials · 2022Article
- pH-Responsive Inorganic/Organic Nanohybrids System for Controlled Nicotinic Acid Drug Release.Molecules (Basel, Switzerland) · 2022Article
- Potential bioactive coating system for high-performance absorbable magnesium bone implants.Bioactive materials · 2022Review
- Advances in coatings on magnesium alloys for cardiovascular stents - A review.Bioactive materials · 2021Review
- Pure Mg-Al Layered Double Hydroxide Film on Magnesium Alloys for Orthopedic Applications.ACS omega · 2021Article
- Corrosion Behavior and Biocompatibility of Diamond-like Carbon-Coated Zinc: An In Vitro Study.ACS omega · 2021Article
- Bioactivity Performance of Pure Mg after Plasma Electrolytic Oxidation in Silicate-Based Solutions.Molecules (Basel, Switzerland) · 2021Article
- A Review on LDH-Smart Functionalization of Anodic Films of Mg Alloys.Nanomaterials (Basel, Switzerland) · 2021Review
- Corrosion protection properties of different inhibitors containing PEO/LDHs composite coating on magnesium alloy AZ31.Scientific reports · 2021Article
- Osteogenesis, angiogenesis and immune response of Mg-Al layered double hydroxide coating on pure Mg.Bioactive materials · 2021Article
- Article
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Authors and funding
6 authors.
Funding
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Abstract
In recent years, magnesium (Mg) alloys show a promising application in clinic as degradable biomaterials. Nevertheless, the poor corrosion resistance of Mg alloys is the main obstacle to their clinical application. Here we successfully seal the pores of plasma electrolytic oxidation (PEO) coating on AZ31 with Mg-Al layered double hydroxide (LDH) via hydrothermal treatment. PEO/LDH composite coating possess a two layer structure, an inner layer made up of PEO coating (~5 μm) and an outer layer of Mg-Al LDH (~2 μm). Electrochemical and hydrogen evolution tests suggest preferable corrosion resistance of the PEO/LDH coating. Cytotoxicity, cell adhesion, live/dead staining and proliferation data of rat bone marrow stem cells (rBMSCs) demonstrate that PEO/LDH coating remarkably enhance the cytocompatibility of the substrate, indicating a potential application in orthopedic surgeries. In addition, hemolysis rate (HR) test shows that the HR value of PEO/LDH coating is 1.10 ± 0.47%, fulfilling the request of clinical application. More importantly, the structure of Mg-Al LDH on the top of PEO coating shows excellent drug delivery ability.
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