Evidence map›Paper›PMID 28811528›Full record

ArticleScientific reports2017

Prenatal hypoxia leads to hypertension, renal renin-angiotensin system activation and exacerbates salt-induced pathology in a sex-specific manner.

S L Walton, H Bielefeldt-Ohmann, R R Singh, J Li, T M Paravicini, M H Little, K M Moritz

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
8.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
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  5. Effects of a postnatal high-salt diet on cardiac function in offspring from hypoxic pregnancies.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
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  11. Early-Life Origins of Metabolic Syndrome: Mechanisms and Preventive Aspects.International journal of molecular sciences · 2021
    Review
  12. Review
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  14. COVID-19 During Development: A Matter of Concern.Frontiers in cell and developmental biology · 2021
    Article
  15. Sex differences and the effects of intrauterine hypoxia on growth and in vivo heart function of fetal guinea pigs.American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
  16. Deletion of hypoxia-responsive microRNA-210 results in a sex-specific decrease in nephron number.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

S L WaltonSchool of Biomedical Sciences, The University of Queensland, St Lucia, Brisbane, Queensland, Australia.ORCID 0000-0002-8099-0272
H Bielefeldt-OhmannSchool of Veterinary Science, The University of Queensland, Gatton, Queensland, Australia.
R R SinghDepartment of Physiology, Monash University, Clayton, Victoria, Australia.
J LiInstitute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland, Australia.
T M ParaviciniSchool of Biomedical Sciences, The University of Queensland, St Lucia, Brisbane, Queensland, Australia.
M H LittleInstitute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland, Australia.
K M MoritzSchool of Biomedical Sciences, The University of Queensland, St Lucia, Brisbane, Queensland, Australia. k.moritz1@uq.edu.au.
The University of Queensland · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prenatal hypoxia is associated with growth restriction and adverse cardiovascular outcomes. Here, we describe renal and cardiovascular outcomes in ageing mouse offspring prenatally exposed to hypoxia (12% O

Indexed as

Prenatal Exposure Delayed EffectsRenin-Angiotensin SystemAge FactorsAnimalsBiopsyBlood PressureCase-Control StudiesDisease Models, AnimalElectrolytesFemaleGene ExpressionHeart Function TestsHypertensionHypoxiaKidneyKidney Function TestsElectrolytesSalts

Identifiers

PMID28811528
PMCPMC5557956
OpenAlexW2744065619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.