Evidence map›Paper›PMID 28811493›Full record

ArticleScientific reports2017

Fragile temporal prediction in patients with schizophrenia is related to minimal self disorders.

Brice Martin, Nicolas Franck, Michel Cermolacce, Agnès Falco, Anabel Benair, Estelle Etienne, Sébastien Weibel, Jennifer T Coull, Anne Giersch

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  11. Perceptual Functioning.Current topics in behavioral neurosciences · 2023
    Article
  12. Article
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  15. Neuroscience of consciousness · 2021
    Review
  16. Article
  17. Testing a neurophenomenological model of basic self disturbance in early psychosis.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2019
    Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brice MartinCentre Ressource de Réhabilitation psychosociale et de remédiation cognitive, Centre Référent Lyonnais en Réhabilitation et en Remédiation cognitive (CL3R) Hôpital du Vinatier; CNRS UMR 5229, Lyon, France.
Nicolas FranckCentre Ressource de Réhabilitation psychosociale et de remédiation cognitive, Centre Référent Lyonnais en Réhabilitation et en Remédiation cognitive (CL3R) Hôpital du Vinatier; CNRS UMR 5229, Lyon, France.
Michel CermolacceService Universitaire de Psychiatrie, Centre Hospitalier Universitaire Ste Marguerite, 13009, Marseille, France.
Agnès FalcoCentre Ressource de Réhabilitation psychosociale et de remédiation cognitive, Centre Référent Lyonnais en Réhabilitation et en Remédiation cognitive (CL3R) Hôpital du Vinatier; CNRS UMR 5229, Lyon, France.
Anabel BenairCentre Ressource de Réhabilitation psychosociale et de remédiation cognitive, Centre Référent Lyonnais en Réhabilitation et en Remédiation cognitive (CL3R) Hôpital du Vinatier; CNRS UMR 5229, Lyon, France.
Estelle EtienneCentre Ressource de Réhabilitation psychosociale et de remédiation cognitive, Centre Référent Lyonnais en Réhabilitation et en Remédiation cognitive (CL3R) Hôpital du Vinatier; CNRS UMR 5229, Lyon, France.
Sébastien WeibelINSERM U1114, Pôle de Psychiatrie, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Centre Hospitalier Régional Universitaire of Strasbourg, Université de Strasbourg, Strasbourg, France.
Jennifer T CoullLaboratoire des Neurosciences Cognitives (UMR 7291), Aix-Marseille Université & CNRS, 3 Place Victor Hugo, 13331, Marseille cedex 3, France.
Anne GierschINSERM U1114, Pôle de Psychiatrie, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Centre Hospitalier Régional Universitaire of Strasbourg, Université de Strasbourg, Strasbourg, France. giersch@unistra.fr.ORCID 0000-0002-8577-6021

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with schizophrenia have difficulty in making sensory predictions, in the time domain, which have been proposed to be related to self-disorders. However experimental evidence is lacking. We examined both voluntary and automatic forms of temporal prediction in 28 patients and 24 matched controls. A visual cue predicted (temporal cue) or not (neutral cue) the time (400 ms/1000 ms) at which a subsequent target was presented. In both patients and controls, RTs were faster for targets presented after long versus short intervals due to the temporal predictability inherent in the elapse of time ("hazard function"). This RT benefit was correlated with scores on the EASE scale, which measures disorders of the self: patients with a high 'self-awareness and presence' score did not show any significant benefit of the hazard function, whereas this ability was preserved in patients with a low score. Moreover, all patients were abnormally sensitive to the presence of "catch" trials (unexpected absence of a target) within a testing block, with RTs actually becoming slower at long versus short intervals. These results indicate fragility in patients' ability to continuously extract temporally predictive information from the elapsing interval. This deficit might contribute to perturbations of the minimal self in patients.

Indexed as

Schizophrenic PsychologyAdultCase-Control StudiesCognitionCuesFemaleHumansMaleMental Status and Dementia TestsReaction TimeSchizophreniaSymptom AssessmentYoung Adult

Identifiers

PMID28811493
PMCPMC5557764

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.