Evidence map›Paper›PMID 28811311›Full record

ArticleDevelopment (Cambridge, England)2017

Linking the environment, DAF-7/TGFβ signaling and LAG-2/DSL ligand expression in the germline stem cell niche.

Olga Pekar, Maria C Ow, Kailyn Y Hui, Marcus B Noyes, Sarah E Hall, E Jane Albert Hubbard

Open access · greenAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
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  9. ThemicroPublication biology · 2025
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  15. Article
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  17. Analysis of the C. elegans Germline Stem Cell Pool.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  18. Article
  19. TheeLife · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Olga PekarSkirball Institute of Biomolecular Medicine and Department of Cell Biology, NYU School of Medicine, New York, NY 10016, USA.
Maria C OwDepartment of Biology, Syracuse University, Syracuse, NY 13244, USA.
Kailyn Y HuiInstitute for Systems Genetics, NYU School of Medicine, New York, NY 10016, USA.
Marcus B NoyesInstitute for Systems Genetics, NYU School of Medicine, New York, NY 10016, USA.
Sarah E HallDepartment of Biology, Syracuse University, Syracuse, NY 13244, USA.
E Jane Albert HubbardSkirball Institute of Biomolecular Medicine and Department of Cell Biology, NYU School of Medicine, New York, NY 10016, USA jane.hubbard@med.nyu.edu.ORCID 0000-0001-5893-7232
Institute for Systems Biology · USNew York University · USSyracuse University · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
CONTROL ONSET OF MEIOSIS IN C. ELEGANSR01GM061706 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HUBBARD, E. JANE ALBERT · 2000 to 2018
$5.4M
" TGF-beta and sensory regulation of germline development in C. elegans".R01GM102254 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HUBBARD, E. JANE ALBERT · 2012 to 2015
$1.3M
Environmental programming of neuronal gene expression by endogenous RNAi pathwaysR15GM111094 · NIGMS · SYRACUSE UNIVERSITY · PI HALL, SARAH E · 2016 to 2016
$446k
Zeiss LSM 710 confocal microscopeS10RR024708 · NCRR · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NANCE, JEREMY · 2009 to 2009
$438k
NCI NIH HHS P30 CA016087NCRR NIH HHS S10 RR024708NIGMS NIH HHS R01 GM061706NIGMS NIH HHS R01 GM102254NIGMS NIH HHS R15 GM111094NIH HHS P40 OD010440
6 · The paper itself

Abstract

The developmental accumulation of proliferative germ cells in the

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsChromatin ImmunoprecipitationIn Situ HybridizationSignal TransductionStem Cell NicheTransforming Growth Factor betaCaenorhabditis elegans ProteinsDAF-7 protein, C elegansTransforming Growth Factor betaC. elegansDAF-3GLP-1/NotchSMADSno-Ski

Identifiers

PMID28811311
PMCPMC5592813
OpenAlexW2749953799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.