Evidence map›Paper›PMID 28811280›Full record

ArticleThe Journal of cell biology2017

DAN (NBL1) promotes collective neural crest migration by restraining uncontrolled invasion.

Rebecca McLennan, Caleb M Bailey, Linus J Schumacher, Jessica M Teddy, Jason A Morrison, Jennifer C Kasemeier-Kulesa, Lauren A Wolfe, Madeline M Gogol, Ruth E Baker, Philip K Maini and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Collective migration modes in development, tissue repair and cancer.Nature reviews. Molecular cell biology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Rules of collective migration: from the wildebeest to the neural crest.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Rebecca McLennanStowers Institute for Medical Research, Kansas City, MO.
Caleb M BaileyDepartment of Biology, Brigham Young University-Idaho, Rexburg, ID.
Linus J SchumacherDepartment of Life Sciences, Imperial College London, London, England, UK.
Jessica M TeddyStowers Institute for Medical Research, Kansas City, MO.
Jason A MorrisonStowers Institute for Medical Research, Kansas City, MO.
Jennifer C Kasemeier-KulesaStowers Institute for Medical Research, Kansas City, MO.
Lauren A WolfeStowers Institute for Medical Research, Kansas City, MO.
Madeline M GogolStowers Institute for Medical Research, Kansas City, MO.
Ruth E BakerWolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, England, UK.
Philip K MainiWolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, England, UK.
Paul M KulesaStowers Institute for Medical Research, Kansas City, MO pmk@stowers.org.
Stowers Institute for Medical Research · USUniversity of Oxford · GBBrigham Young University - Idaho · USImperial College London · GB

Funding

Examining Signals That Sculpt Cranial Neural Crest MigrationR03HD089190 · NICHD · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI KULESA, PAUL · 2017 to 2018
$165k
NICHD NIH HHS R03 HD089190
6 · The paper itself

Abstract

Neural crest cells are both highly migratory and significant to vertebrate organogenesis. However, the signals that regulate neural crest cell migration remain unclear. In this study, we test the function of differential screening-selected gene aberrant in neuroblastoma (DAN), a bone morphogenetic protein (BMP) antagonist we detected by analysis of the chick cranial mesoderm. Our analysis shows that, before neural crest cell exit from the hindbrain,

Indexed as

Cell MovementSignal TransductionAnimalsAvian ProteinsBone Morphogenetic ProteinsChick EmbryoChickensMelanomaNeoplasm InvasivenessNeural CrestTumor Suppressor ProteinsAvian ProteinsBone Morphogenetic ProteinsTumor Suppressor Proteins

Identifiers

PMID28811280
PMCPMC5626539
OpenAlexW2746498552

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.