Evidence map›Paper›PMID 28810847›Full record

ArticleBMC pulmonary medicine2017

FEV

Jaime E Hart, Rebekah Goldstein, Palak Walia, Merilee Teylan, Antonio Lazzari, Carlos G Tun, Eric Garshick

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04500223 (The Effect of Neck Stabilization Exercise Plus Cardiopulmonary Rehabilitation on Pulmonary Function of SCI), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04500223 nacompletednot on this mapstarted 2020, after this paper: background citation

The Effect of Neck Stabilization Exercise Plus Cardiopulmonary Rehabilitation on Pulmonary Function of SCI

TypeinterventionalSponsorTaoyuan General HospitalRan2020 to 2021Enrolled13ConditionsSpinal Cord InjuryArmsCervical Cranioflexion exercise plus cardiopulmonary exercise, Cervical stretch exercise plus cardiopulmonary rehabilitation
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. HAntioxidants (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Does fetal leptin and adiponectin influence children's lung function and risk of wheeze?Journal of developmental origins of health and disease · 2021
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Jaime E HartChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 401 Park Drive, Landmark Center 3rd Floor West, Boston, MA, 02215, USA. rejch@channing.harvard.edu.
Rebekah GoldsteinResearch and Development Service, VA Boston Healthcare System, Boston, MA, USA.
Palak WaliaResearch and Development Service, VA Boston Healthcare System, Boston, MA, USA.
Merilee TeylanResearch and Development Service, VA Boston Healthcare System, Boston, MA, USA.
Antonio LazzariDivison of Primary Care and Rheumatology Section, VA Boston Healthcare System, Boston University School of Medicine, Boston, MA, USA.
Carlos G TunDepartment of Physical Medicine and Rehabilitation, VA Boston Healthcare System, Boston, MA, USA.
Eric GarshickChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, 401 Park Drive, Landmark Center 3rd Floor West, Boston, MA, 02215, USA.
VA Boston Healthcare System · USBoston University · USBrigham and Women's Hospital · USRoxbury Community College · USUniversity of Washington · US

Funding

Adiposity and Bone Loss in Spinal Cord InjuryR01AR059270 · NIAMS · SPAULDING REHABILITATION HOSPITAL · PI MORSE, LESLIE R. · 2010 to 2014
$3.0M
Vitamin D, Respiratory Function, and Illness in Chronic SCII01RX000792 · VA · VA BOSTON HEALTH CARE SYSTEM · PI GARSHICK, ERIC · 2014 to 2016
–
NIAMS NIH HHS R01 AR059270RRD VA I01 RX000792
6 · The paper itself

Abstract

backgroundSystemic inflammation has been associated with reduced pulmonary function in individuals with and without chronic medical conditions. Individuals with chronic spinal cord injury (SCI) have clinical characteristics that promote systemic inflammation and also have reduced pulmonary function. We sought to assess the associations between biomarkers of systemic inflammation with pulmonary function in a chronic SCI cohort, adjusting for other potential confounding factors.

methodsParticipants (n = 311) provided a blood sample, completed a respiratory health questionnaire, and underwent spirometry. Linear regression methods were used to assess cross-sectional associations between plasma C-reactive protein (CRP) and interleukin-6 (IL-6) with forced expiratory volume in one second (FEV

resultsThere were statistically significant inverse relationships between plasma CRP and IL-6 assessed in quartiles or continuously with FEV

conclusionPlasma CRP and IL-6 in individuals with chronic SCI are inversely associated with FEV

Indexed as

AdultAgedCohort StudiesC-Reactive ProteinFemaleForced Expiratory VolumeHumansInflammationInterleukin-6Linear ModelsLungMaleMiddle AgedSpinal Cord InjuriesSpirometryVital CapacityC-Reactive ProteinIL6 protein, humanInterleukin-6Chronic spinal cord injuryCRPIl-6Pulmonary functionSystemic inflammation

Identifiers

PMID28810847
PMCPMC5558736
OpenAlexW2747349129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.