Evidence map›Paper›PMID 28810655›Full record

ArticleExperimental and therapeutic medicine2017

MicroRNA-590-3p enhances the radioresistance in glioblastoma cells by targeting LRIG1.

Long Chen, Wenhua Wang, Shengqiang Zhu, Xuegang Jin, Jian Wang, Jianfang Zhu, Youxin Zhou

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Deregulated MicroRNA Signature Following Glioblastoma Irradiation.Cancer control : journal of the Moffitt Cancer Center
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Long ChenDepartment of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China.
Wenhua WangDepartment of Neurosurgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Kunshan, Jiangsu 215300, P.R. China.
Shengqiang ZhuDepartment of Neurosurgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Kunshan, Jiangsu 215300, P.R. China.
Xuegang JinDepartment of Neurosurgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Kunshan, Jiangsu 215300, P.R. China.
Jian WangDepartment of Neurosurgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Kunshan, Jiangsu 215300, P.R. China.
Jianfang ZhuDepartment of Neurosurgery, The Affiliated Hospital of Nanjing University of Chinese Medicine, Kunshan, Jiangsu 215300, P.R. China.
Youxin ZhouDepartment of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. China.
Nanjing University of Chinese Medicine · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

microRNA (miR)-590 has been found to serve potential roles in cancer development; however, the expression and function of miR-590 in human gliomas remains to be elucidated. The present study aimed to investigate the expression of miR-590 in human glioma tissues and radioresistant human glioblastoma cells (U251R), and to determine the effect and related molecular mechanism of miR-590-3p on the radiosensitivity of U251R cells

Indexed as

glioblastomaleucine-rich repeats and immunoglobulin-like domains protein 1microRNA-590-3pradiosensitivity

Identifiers

PMID28810655
PMCPMC5526158
OpenAlexW2731513336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.