Evidence map›Paper›PMID 28810159›Full record

ArticleThe International journal on drug policy2017

Hair testing to assess both known and unknown use of drugs amongst ecstasy users in the electronic dance music scene.

Joseph J Palamar, Alberto Salomone, Enrico Gerace, Daniele Di Corcia, Marco Vincenti, Charles M Cleland

Registry-linked trialAbstract read
In one paragraph

Article in The International journal on drug policy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04155281 (Consumption of New Psychoactive Substances in Intoxicated Patients During the Winter Activities), which is not on this map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04155281 completednot on this mapstarted 2020, after this paper: background citation

Consumption of New Psychoactive Substances in Intoxicated Patients During the Winter Activities

TypeobservationalSponsorUniversity Hospital, GrenobleRan2020 to 2023Enrolled87ConditionsAcute Intoxication, Psychoactive Substance UseArmsurine analysis
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. Tusi: a new ketamine concoction complicating the drug landscape.The American journal of drug and alcohol abuse · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joseph J PalamarNew York University Langone Medical Center, Department of Population Health, New York, NY, USA; Center for Drug Use and HIV Research, New York University Rory Meyers College of Nursing, New York, NY, USA. Electronic address: joseph.palamar@nyumc.org.
Alberto SalomoneCentro Regionale Antidoping e di Tossicologia "A. Bertinaria", Orbassano, Turin, Italy.
Enrico GeraceCentro Regionale Antidoping e di Tossicologia "A. Bertinaria", Orbassano, Turin, Italy.
Daniele Di CorciaCentro Regionale Antidoping e di Tossicologia "A. Bertinaria", Orbassano, Turin, Italy.
Marco VincentiCentro Regionale Antidoping e di Tossicologia "A. Bertinaria", Orbassano, Turin, Italy; Dipartimento di Chimica, Università di Torino, Turin, Italy.
Charles M ClelandCenter for Drug Use and HIV Research, New York University Rory Meyers College of Nursing, New York, NY, USA; New York University Rory Meyers College of Nursing, New York, NY, USA.

Funding

Transdisciplinary Theoretical Svnthesis and Development CoreP30DA011041 · NIDA · NEW YORK UNIVERSITY · PI Holly Hagan · 1998 to 2026
$38.9M
Development of a Rapid Survey to Detect Use of New and Emerging DrugsK01DA038800 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PALAMAR, JOSEPH J · 2015 to 2019
$879k
NIDA NIH HHS K01 DA038800NIDA NIH HHS P30 DA011041
6 · The paper itself

Abstract

backgroundData on both known and unknown drug use in the electronic dance music (EDM) scene is important to inform prevention and harm reduction. While surveys are the most common method of querying drug use, additional biological data can help validate use and detect unknown/unintentional use of drugs such as new psychoactive substances (NPS). We sought to determine the extent of both known and unknown use of various substances in this high-risk scene.

methodsWe hair-tested 90 self-reported past-year ecstasy/MDMA/Molly users attending EDM parties in New York City during the summer of 2016 using UHPLC-MS/MS. Results were compared to self-reported past-year use.

resultsThree quarters (74.4%) tested positive for MDMA, a third (33.3%) tested positive for an NPS, and 27.8% tested positive specifically for one or more synthetic cathinones (e.g., butylone, ethylone, pentylone, methylone, alpha-PVP). Half (51.1%) of participants tested positive for a drug not self-reported, with most testing positive for synthetic cathinones (72.0%), methamphetamine (69.0%), other NPS stimulants (e.g., 4-FA, 5/6-APB; 66.7%), or new dissociatives (e.g., methoxetamine, diphenidine; 60.0%). Attending parties every other week or more often, reporting higher-frequency ecstasy pill use, having tested one's ecstasy, and having found out one's ecstasy was adulterated, were risk factors for testing positive for synthetic cathinones and NPS in general.

conclusionHair testing appears to be a valuable addition to drug epidemiology studies. Many EDM party attendees-even those who test their ecstasy-are unknowingly using NPS and/or other drugs. Prevention information and harm reduction may help reduce unknown/unintentional use.

Indexed as

AdolescentAdultChromatography, High Pressure LiquidDancingFemaleHairHallucinogensHarm ReductionHumansIllicit DrugsMaleNew York CityN-Methyl-3,4-methylenedioxyamphetamineSelf ReportSubstance Abuse DetectionSubstance-Related DisordersHallucinogensIllicit DrugsN-Methyl-3,4-methylenedioxyamphetamineAdulterantsHair-testingMDMANew psychoactive substancesSynthetic cathinones

Identifiers

PMID28810159
PMCPMC5601020

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.