Evidence map›Paper›PMID 28809987›Full record

ArticleLab on a chip2017

Label-free ferrohydrodynamic cell separation of circulating tumor cells.

Wujun Zhao, Rui Cheng, Brittany D Jenkins, Taotao Zhu, Nneoma E Okonkwo, Courtney E Jones, Melissa B Davis, Sravan K Kavuri, Zhonglin Hao, Carsten Schroeder and 1 more

Abstract read
In one paragraph

Article in Lab on a chip, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  4. Review
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  6. ViaChip for Size-based Enrichment of Viable Cells.Sensors and actuators. B, Chemical · 2022
    Article
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  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wujun ZhaoDepartment of Chemistry, The University of Georgia, Athens, GA 30602, USA.
Rui Cheng
Brittany D Jenkins
Taotao Zhu
Nneoma E Okonkwo
Courtney E Jones
Melissa B Davis
Sravan K Kavuri
Zhonglin Hao
Carsten Schroeder
Leidong Mao

Funding

INTEGRATED FERROFLUIDIC MICROCHIP FOR CELL MANIPULATION AND ENRICHMENTR21GM104528 · NIGMS · UNIVERSITY OF GEORGIA · PI CHEN, JI, JANSEN, BEN H. · 2012 to 2014
$625k
NIGMS NIH HHS R21 GM104528
6 · The paper itself

Abstract

Circulating tumor cells (CTCs) have significant implications in both basic cancer research and clinical applications. To address the limited availability of viable CTCs for fundamental and clinical investigations, effective separation of extremely rare CTCs from blood is critical. Ferrohydrodynamic cell separation (FCS), a label-free method that conducted cell sorting based on cell size difference in biocompatible ferrofluids, has thus far not been able to enrich low-concentration CTCs from cancer patients' blood because of technical challenges associated with processing clinical samples. In this study, we demonstrated the development of a laminar-flow microfluidic FCS device that was capable of enriching rare CTCs from patients' blood in a biocompatible manner with a high throughput (6 mL h

Indexed as

Neoplastic Cells, CirculatingCell Line, TumorCell SeparationCell SurvivalEquipment DesignHigh-Throughput Screening AssaysHumansMagnetite NanoparticlesMicrofluidic Analytical TechniquesMagnetite Nanoparticles

Identifiers

PMID28809987
PMCPMC5595667

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.