ArticleTranslational psychiatry2017
Repeated exposure to systemic inflammation and risk of new depressive symptoms among older adults.
Article in Translational psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Psychological factors associated with postoperative cognitive outcomes in older adults: a systematic review and meta-analysis.British journal of anaesthesia · 2026Pooled it
- Effects of a diverse prebiotic fibre blend on inflammation, the gut microbiota and affective symptoms in metabolic syndrome: a pilot open-label randomised controlled trial.The British journal of nutrition · 2024Trial
- Peripheral Blood Inflammatory Cytokine Factors Expressions are Associated with Response to Acupuncture Therapy in Postpartum Depression Patients.Journal of inflammation research · 2023Trial
- CD4Frontiers in psychiatry · 2026Article
- Comparative effect of vortioxetine and sertraline on clinical and inflammatory profile in Parkinson's disease with comorbid depression.Frontiers in neuroscience · 2026Article
- Insomnia and Inflammation Conspire to Heighten Depression Risk: Implications for Treatment and Prevention of Mood Disorders.Biological psychiatry · 2025Review
- An interoceptive model of energy allostasis linking metabolic and mental health.Science advances · 2025Review
- Moderating effect of sleep duration on the association between the accumulation of chronic diseases and late-life depressive symptoms among Chinese older adults.Geriatrics & gerontology international · 2025Article
- Associations Between Oral Microbiota Pathogens and Elevated Depressive and Anxiety Symptoms in Men.Depression and anxiety · 2025Article
- The association between Children's sleep quality and juvenile idiopathic arthritis.Frontiers in pediatrics · 2025Article
- Associations between uric acid and depressive symptoms, and the mediating role of immunoinflammatory: Findings from rural older adults.Brain, behavior, & immunity - health · 2024Article
- From movement to motivation: a proposed framework to understand the antidepressant effect of exercise.Translational psychiatry · 2024Review
- Chronic inflammation is associated with worsening working memory performance: Preliminary evidence from a diverse, longitudinal cohort of adolescents and young adults.Psychoneuroendocrinology · 2024Article
- Bidirectional relationship between C-reactive protein and depressive symptoms considering cumulative effect among Chinese middle-aged and older adults.Frontiers in psychiatry · 2024Article
- The prevalence and outcomes of depression in older HIV-positive adults in Northern Tanzania: a longitudinal study.Journal of neurovirology · 2023Article
- Network analysis of the associations between personality traits, cognitive functioning, and inflammatory markers in elderly individuals without dementia.Frontiers in aging neuroscience · 2023Article
- Brain signatures of chronic gut inflammation.Frontiers in psychiatry · 2023Article
- Nature-Based Interventions for Psychological Wellbeing in Long-Term Conditions: A Systematic Review.International journal of environmental research and public health · 2022Review
- Immune targets for therapeutic development in depression: towards precision medicine.Nature reviews. Drug discovery · 2022Review
- Systemic inflammation and emotional responses during the COVID-19 pandemic.Translational psychiatry · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Evidence on systemic inflammation as a risk factor for future depression is inconsistent, possibly due to a lack of regard for persistency of exposure. We examined whether being inflamed on multiple occasions increases risk of new depressive symptoms using prospective data from a population-based sample of adults aged 50 years or older (the English Longitudinal Study of Ageing). Participants with less than four of eight depressive symptoms in 2004/05 and 2008/09 based on the Eight-item Centre for Epidemiologic Studies Depression scale were analysed. The number of occasions with C-reactive protein ⩾3 mg l
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.