ReviewInternational journal of molecular sciences2017
Optogenetic Investigation of Arousal Circuits.
Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed.
- Burst firing creates an attractor in synaptic weight dynamics.PLoS computational biology · 2026Article
- Noradrenergic tuning of arousal is coupled to movement transitions.Cell reports · 2025Article
- Activity Monitoring for Analysis of Sleep inCold Spring Harbor protocols · 2024Article
- Gain control of sensory input across polysynaptic circuitries in mouse visual cortex by a single G protein-coupled receptor type (5-HTNature communications · 2024Article
- A clock-dependent brake for rhythmic arousal in the dorsomedial hypothalamus.Nature communications · 2023Article
- A role of prefrontal cortico-hypothalamic projections in wake promotion.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Evaluation of SAMP8 Mice as a Model for Sleep-Wake and Rhythm Disturbances Associated with Alzheimer's Disease: Impact of Treatment with the Dual Orexin (Hypocretin) Receptor Antagonist Lemborexant.Journal of Alzheimer's disease : JAD · 2021Article
- Separable gain control of ongoing and evoked activity in the visual cortex by serotonergic input.eLife · 2020Article
- New era of optogenetics: from the central to peripheral nervous system.Critical reviews in biochemistry and molecular biology · 2020Review
- Recent advances in understanding the genetics of sleep.F1000Research · 2020Review
- Neural mechanisms of social homeostasis.Annals of the New York Academy of Sciences · 2019Review
- Article
- Article
- Hypocretin as a Hub for Arousal and Motivation.Frontiers in neurology · 2018Review
- Sleep-Wake Cycling and Energy Conservation: Role of Hypocretin and the Lateral Hypothalamus in Dynamic State-Dependent Resource Optimization.Frontiers in neurology · 2018Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Modulation between sleep and wake states is controlled by a number of heterogeneous neuron populations. Due to the topological proximity and genetic co-localization of the neurons underlying sleep-wake state modulation optogenetic methods offer a significant improvement in the ability to benefit from both the precision of genetic targeting and millisecond temporal control. Beginning with an overview of the neuron populations mediating arousal, this review outlines the progress that has been made in the investigation of arousal circuits since the incorporation of optogenetic techniques and the first in vivo application of optogenetic stimulation in hypocretin neurons in the lateral hypothalamus. This overview is followed by a discussion of the future progress that can be made by incorporating more recent technological developments into the research of neural circuits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.