Evidence map›Paper›PMID 28809770›Full record

Observational studySexually transmitted diseases2017

Uptake of Home-Based Syphilis and Human Immunodeficiency Virus Testing Among Male Partners of Pregnant Women in Western Kenya.

Jennifer Mark, John Kinuthia, Alison C Roxby, Daisy Krakowiak, Alfred Osoti, Barbra A Richardson, Molly Ann Gone, Victor Asila, Saloni Parikh, Carey Farquhar

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Sexually transmitted diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Jennifer MarkFrom the *Department of Epidemiology, University of Washington, Seattle, WA; †Departments of Research and Programs, ‡Department of Reproductive Health, Kenyatta National Hospital, Nairobi, Kenya; §Department of Obstetrics and Gynaecology, University of Nairobi; Nairobi, Kenya; ¶Departments of Medicine, ∥Global Health, **Biostatistics, and ††Computer Science and Engineering, University of Washington, Seattle, WA.
John Kinuthia
Alison C Roxby
Daisy Krakowiak
Alfred Osoti
Barbra A Richardson
Molly Ann Gone
Victor Asila
Saloni Parikh
Carey Farquhar
University of Nairobi · KEKenyatta National Hospital · KEUniversity of Washington · US

Funding

NPGH LEADERs YR12: OBSSR (Greenberg, Ngwafong Mukere) & NIBIB (Lee)D43TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI Dibyadyuti Datta, Chandy C. John · 2017 to 2026
$15.2M
Northern/Pacific Universities Global Health Research Training ConsortiumR25TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI KOLARS, JOSEPH C., NERURKAR, VIVEK RAMCHANDRA · 2012 to 2016
$5.9M
HIV Testing and Educating Male Partners to Improve Maternal and Infant OutcomesR01HD075108 · NICHD · UNIVERSITY OF WASHINGTON · PI FARQUHAR, CAREY · 2012 to 2013
$684k
Immune activation during pregnancy and contraception in HIV-infected Kenyan womenK23HD071788 · NICHD · UNIVERSITY OF WASHINGTON · PI ROXBY, ALISON CHRISTINA · 2012 to 2016
$648k
FIC NIH HHS D43 TW009345FIC NIH HHS R25 TW009345NICHD NIH HHS K23 HD071788NICHD NIH HHS R01 HD075108
6 · The paper itself

Abstract

backgroundFew men are tested for syphilis or human immunodeficiency virus (HIV) during their partner's pregnancy, a high-risk period for HIV and syphilis transmission. Offering home-based rapid testing of syphilis to couples during pregnancy can support prevention efforts to reduce transmission of sexually transmitted diseases and adverse pregnancy outcomes.

methodsWe assessed men's uptake of paired (separate tests, single blood draw) point-of-care syphilis and HIV tests within a randomized controlled trial of pregnant women who received clinic or home partner HIV testing. We evaluated acceptance of paired HIV-syphilis testing during pregnancy or at 6 months postpartum, and evaluated whether addition of syphilis testing affected the uptake of HIV testing among men.

resultsOf 601 women, we were unable to meet 101 male partners, and 180 tested before syphilis tests were available. Paired syphilis and HIV testing was offered at home to 80 men during pregnancy and to 230 men postpartum. For syphilis, 93% of men agreed to test during pregnancy and 98% agreed postpartum. For paired syphilis and HIV testing, 91% of men tested for both during pregnancy and 96% tested postpartum. Before syphilis test introduction, 96% of men accepted HIV testing, compared with 95% of men who accepted HIV testing when paired testing was offered.

conclusionsUptake of syphilis and HIV testing was high among male partners offered couple testing at home. Introducing syphilis testing did not adversely affect HIV testing among men. Point-of-care diagnostics outside facilities can increase testing of male partners who rarely accompany women to antenatal clinics.

Indexed as

HIV InfectionsPoint-of-Care SystemsPregnancy Complications, InfectiousSexually Transmitted DiseasesSexual PartnersSyphilisAdultCohort StudiesFemaleHumansKenyaMalePostpartum PeriodPregnancy

Identifiers

PMID28809770
PMCPMC5657390
OpenAlexW2645407266

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.