Evidence map›Paper›PMID 28809158›Full record

ArticleeLife2017

Germ cell connectivity enhances cell death in response to DNA damage in the

Kevin L Lu, Yukiko M Yamashita

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Niche-dependent modular regulation of the stem cell transcriptome separates cell identity and potential.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Rewinding the clock: mechanisms of dedifferentiation.Current opinion in genetics & development · 2025
    Review
  11. Hurdles of Sperm Success: Exploring the Role of DNases.International journal of molecular sciences · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. rDNA magnification is a unique feature of germline stem cells.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Branched germline cysts and female-specific cyst fragmentation facilitate oocyte determination in mice.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kevin L LuLife Sciences Institute, University of Michigan, Ann Arbor, United States.
Yukiko M YamashitaLife Sciences Institute, University of Michigan, Ann Arbor, United States.ORCID 0000-0001-5541-0216
Howard Hughes Medical Institute · USUniversity of Michigan · US

Funding

MICHIGAN MEDICAL SCIENTIST TRAINING PROGRAMT32GM007863 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 1985 to 2024
$38.3M
Career Training in Reproductive BiologyT32HD079342 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Suzanne M MOENTER · 2014 to 2026
$2.3M
Niche-mediated regulation of asymmetric stem cell divisionR01GM118308 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YAMASHITA, YUKIKO · 2016 to 2019
$1.2M
Nucleolar fragmentation in Drosophila germline stem cells during agingF30AG050398 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LU, KEVIN LU · 2015 to 2017
$54k
Howard Hughes Medical InstituteNIA NIH HHS F30 AG050398NICHD NIH HHS T32 HD079342NIGMS NIH HHS R01 GM118308NIGMS NIH HHS T32 GM007863
6 · The paper itself

Abstract

Two broadly known characteristics of germ cells in many organisms are their development as a 'cyst' of interconnected cells and their high sensitivity to DNA damage. Here we provide evidence that in the

Indexed as

Cell CommunicationCell DeathDNA DamageAnimalsDrosophilaGerm CellsMaleTestisdevelopmental biologyD. melanogasterDNA damagefusomegerm cell cystgerm cellsstem cells

Identifiers

PMID28809158
PMCPMC5577909
OpenAlexW2610617015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.