ArticlePhytotherapy research : PTR2017
Acylated Iridoids and Rhamnopyranoses from Premna odorata (Lamiaceae) as Novel Mesenchymal-Epithelial Transition Factor Receptor Inhibitors for the Control of Breast Cancer.
Article in Phytotherapy research : PTR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
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- Scabicidal Potential of Coconut Seed Extract in Rabbits via Downregulating Inflammatory/Immune Cross Talk: A Comprehensive Phytochemical/GC-MS and In Silico Proof.Antibiotics (Basel, Switzerland) · 2022Article
- Amelioration of aluminum-induced hepatic and nephrotoxicity by Premna odorata extract is mediated by lowering MMP9 and TGF-β gene alterations in Wistar rat.Environmental science and pollution research international · 2022Article
- New Halogenated Compounds fromMolecules (Basel, Switzerland) · 2022Article
- The anti-Alzheimer potential ofRSC advances · 2022Article
- Premna odorata extract as a protective agent on neurotoxic effect of aluminum: neurochemical, molecular, and histopathological alterations.Environmental science and pollution research international · 2021Article
- A review of medicinal plant of Middle East and North Africa (MENA) region as source in tuberculosis drug discovery.Saudi journal of biological sciences · 2020Review
- Anti-Inflammatory and Antioxidant Activities of Terpene- and Polyphenol-RichMolecules (Basel, Switzerland) · 2020Article
- Triple-negative breast cancer suppressive activities, antioxidants and pharmacophore model of new acylated rhamnopyranoses fromRSC advances · 2020Article
- Metabolomic Profiling and Cytotoxic Tetrahydrofurofuran Lignans Investigations fromMetabolites · 2019Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
Phytochemical investigation of Premna odorata Blanco, Lamiaceae, leaves afforded three new acylated iridoid glycosides 1-3 and two new acylated rhamnopyranoses 9 and 10, in addition to ten known compounds. The structures of the new compounds were confirmed using extensive 1D and 2D NMR analysis. Molecular modeling study suggested the potential of the acylated rhamnopyranoses to bind at the c-Met kinase domain. Cell-free Z'-LYTE™ assay testing revealed the good c-Met phosphorylation inhibitory activity of 9, followed by 8, and 10, with IC
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Registered trials
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