Evidence map›Paper›PMID 28808938›Full record

ReviewPaediatric drugs2017

Advances in Vaccines to Prevent Viral Respiratory Illnesses in Children.

Aleisha J Anderson, Tom L Snelling, Hannah C Moore, Christopher C Blyth

Abstract readReview
PubMed Publisher
In one paragraph

Review in Paediatric drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Distribution and Drug Resistance of Bacterial Pathogens Associated with Lower Respiratory Tract Infection in Children and the Effect of COVID-19 on the Distribution of Pathogens.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. A multifaceted approach to RSV vaccination.Human vaccines & immunotherapeutics · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Aleisha J AndersonDepartment of Infectious Diseases, Princess Margaret Hospital, Roberts Rd, Subiaco, WA, Australia.
Tom L SnellingDepartment of Infectious Diseases, Princess Margaret Hospital, Roberts Rd, Subiaco, WA, Australia.
Hannah C MooreWesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, Roberts Rd, Subiaco, WA, Australia.
Christopher C BlythDepartment of Infectious Diseases, Princess Margaret Hospital, Roberts Rd, Subiaco, WA, Australia. christopher.blyth@uwa.edu.au.
Princess Margaret Hospital for Children · AUThe Kids Research Institute Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood vaccination has played a critical role in the reduction of morbidity and mortality from communicable diseases, including specific respiratory pathogens. Acute lower respiratory infection (ALRI) of both bacterial and viral aetiology continues to impact global child health. Key bacterial pathogens including Streptococcus pneumoniae and Haemophilus influenza type b are specifically targeted with current vaccination programmes, while at present there are less effective strategies for the prevention of viral disease. Influenza vaccines, including both live attenuated intranasal vaccines and inactivated influenza vaccines, are limited by seasonal strain variation and unsustained immunity. Research into the development of a universal influenza vaccine is ongoing; potential targets are the conserved regions of the virus such as the M2e antigen and hemagglutinin stalk. Respiratory syncytial virus (RSV) and parainfluenza virus 3 (PIV3) are the viral pathogens most commonly causing ALRI in children, particularly the infant population. Currently, no vaccine exists for either virus. Over the last decade, promising advances have been made. Protection of neonates via maternal RSV immunisation is being assessed in a phase III clinical trial, with many other candidates for RSV and PIV3 at less advanced stages of development.

Indexed as

Viral VaccinesAdministration, IntranasalChildHumansInfluenza, HumanInfluenza VaccinesParainfluenza VaccinesRespiratory Syncytial Virus VaccinesRespiratory Tract InfectionsVaccinationVaccines, AttenuatedInfluenza VaccinesParainfluenza VaccinesRespiratory Syncytial Virus VaccinesVaccines, AttenuatedViral Vaccines

Identifiers

PMID28808938
OpenAlexW2746759276

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.