ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2017
Effect of Multimodal Analgesia on Opioid Use After Open Ventral Hernia Repair.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03792295 (The Effect of Multimodal Pain Therapy After Hernia Repair), which is not on this map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Multimodal Pain Therapy After Hernia Repair
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The European Hernia Society Prehabilitation Project: a systematic review of patient prehabilitation prior to ventral hernia surgery.Hernia : the journal of hernias and abdominal wall surgery · 2022Pooled it
- Should enhanced recovery after surgery (ERAS) pathways be preferred over standard practice for patients undergoing abdominal wall reconstruction? A systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2021Pooled it
- Enhanced recovery after abdominal wall reconstruction: a systematic review and meta-analysis.Surgical endoscopy · 2021Pooled it
- Association of robotic surgical approach with decreased inpatient opioid exposure after abdominal wall reconstruction: a retrospective cohort study.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Posterior Flap Hernioplasty: A Cost-effective Alternative to Transversus Abdominis Release in Complex Ventral Hernias.Plastic and reconstructive surgery. Global open · 2026Article
- Characterizing patterns of opioid prescribing after outpatient ventral hernia repair with mesh.Hernia : the journal of hernias and abdominal wall surgery · 2024Review
- Consensus in ERAS protocols for ventral hernia repair: evidence-based recommendations from the ACHQC QI Committee.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- Predictors of postoperative opioid use in ventral and incisional hernia repair.Surgical endoscopy · 2024Article
- The persistent benefits of decreasing default pill counts for postoperative narcotic prescriptions.PloS one · 2024Article
- A cost-conscious establishment of a robotic abdominal wall reconstruction program in a publicly funded healthcare system.Hernia : the journal of hernias and abdominal wall surgery · 2023Article
- Utilization of a National Registry to influence opioid prescribing behavior after hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- Postoperative Pain Management in Enhanced Recovery Pathways.Journal of pain research · 2022Review
- Comparative effectiveness of surgeon-performed transversus abdominis plane blocks and epidural catheters following open hernia repair with transversus abdominis release.Hernia : the journal of hernias and abdominal wall surgery · 2021Article
- Impact of Enhanced Recovery After Surgery on Postoperative Outcomes for Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.Annals of surgical oncology · 2021Article
- Recovery after laparoscopic parastomal hernia repair.Surgical endoscopy · 2021Article
- The Implementation of an Acute Pain Service for Patients Undergoing Open Ventral Hernia Repair with Mesh and Abdominal Wall Reconstruction.World journal of surgery · 2021Article
- The contribution of specific enhanced recovery after surgery (ERAS) protocol elements to reduced length of hospital stay after ventral hernia repair.Surgical endoscopy · 2020Article
- Short-term safety of preoperative administration of botulinum toxin A for the treatment of large ventral hernia with loss of domain.Hernia : the journal of hernias and abdominal wall surgery · 2020Article
- Enhanced recovery after surgical repair of incisional hernias.Hernia : the journal of hernias and abdominal wall surgery · 2020Review
- Perioperative factors associated with pain following open ventral hernia repair.Surgical endoscopy · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is limited data on enhanced recovery after surgery (ERAS) protocols after ventral hernia repair (VHR). This study reports the impact of multimodal analgesia on opioid use after open VHR.
methodsRetrospective review of open VHR treated during the initial 6 months after ERAS implementation. Protocol focused on opioid sparing using intraoperative ketamine and/or lidocaine infusion, selective epidural anesthesia, and postoperative ketamine infusion, ketorolac, and acetaminophen. Four groups were analyzed: 1-ERAS protocol with epidural analgesia, 2-historical controls with epidural analgesia prior to ERAS, 3-ERAS protocol without epidural, and 4-historical controls without epidural analgesia, prior to ERAS. Continuous variables were analyzed using ANOVA or Kruskal-Wallis tests, and subgroup analysis using Student's t test or Mann-Whitney U test. Discrete variables were analyzed using Pearson's chi-square test or Fisher's exact test.
resultsPatients differed in hernia width, but were similar in comorbidity and operative technique. There was no difference in length of stay or readmission. Use of ERAS nearly eliminated patient-controlled analgesia use (group 1, 2.7%; group 2, 68.4%; group 3, 0%; group 4, 65.7%; p < 0.001). ERAS significantly reduced narcotic requirements on postoperative days 0, 1, and 2 (p < 0.001). To account for the bias of selective epidural analgesia, groups 1 and 2 (epidural) and groups 3 and 4 (no epidural) were compared separately. Opioid requirement and PCA use remained significantly lower in patients in the ERAS pathway.
conclusionImplementation of multimodal analgesia in the perioperative and postoperative setting significantly reduced opioid use after VHR.
Indexed as
Identifiers
28808868What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.