Evidence map›Paper›PMID 28808858›Full record

ReviewCurrent heart failure reports2017

Vitamin D and Heart Failure.

D Marshall Brinkley, Omair M Ali, Sandip K Zalawadiya, Thomas J Wang

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Current heart failure reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Vitamin D-Parathyroid Hormone-Fibroblast Growth Factor 23 Axis and Cardiac Remodeling.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
    Review
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  7. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

D Marshall BrinkleyDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, 2220 Pierce Avenue; Preston Research Building, Suite 383, Nashville, TN, 37232-6300, USA.
Omair M AliDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, 2220 Pierce Avenue; Preston Research Building, Suite 383, Nashville, TN, 37232-6300, USA.
Sandip K ZalawadiyaDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, 2220 Pierce Avenue; Preston Research Building, Suite 383, Nashville, TN, 37232-6300, USA.
Thomas J WangDivision of Cardiovascular Medicine, Vanderbilt University Medical Center, 2220 Pierce Avenue; Preston Research Building, Suite 383, Nashville, TN, 37232-6300, USA. thomas.j.wang@vanderbilt.edu.
Preston University · USVanderbilt University Medical Center · US

Funding

Impact of vitamin D supplementation on cardiac structure and functionR01HL112746 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI THADHANI, RAVI, WANG, THOMAS J. · 2012 to 2015
$1.2M
NHLBI NIH HHS R01 HL112746
6 · The paper itself

Abstract

purposeVitamin D is principally known for its role in calcium homeostasis, but preclinical studies implicate multiple pathways through which vitamin D may affect cardiovascular function and influence risk for heart failure. Many adults with cardiovascular disease have low vitamin D status, making it a potential therapeutic target. We review the rationale and potential role of vitamin D supplementation in the prevention and treatment of chronic heart failure. RECENT

findingsSubstantial observational evidence has associated low vitamin D status with the risk of heart failure, ventricular remodeling, and clinical outcomes in heart failure, including mortality. However, trials assessing the influence of vitamin D supplementation on surrogate markers and clinical outcomes in heart failure have generally been small and inconclusive. There are insufficient data to recommend routine assessment or supplementation of vitamin D for the prevention or treatment of chronic heart failure. Prospective trials powered for clinical outcomes are warranted.

Indexed as

Dietary SupplementsHeart FailureHumansRisk FactorsVentricular RemodelingVitamin DVitaminsVitamin DVitaminsCardiovascular diseaseHeart failureOutcomesVitamin D

Identifiers

PMID28808858
OpenAlexW2749941268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.