Evidence map›Paper›PMID 28808847›Full record

Trial reportInternational urology and nephrology2017

Evaluation of hyoscine N-butyl bromide efficacy on the prevention of catheter-related bladder discomfort after transurethral resection of prostate: a randomized, double-blind control trial.

Golnar Sabetian, Farid Zand, Elham Asadpour, Mohammad Ghorbani, Pourya Adibi, Mohammad Mehdi Hosseini, Shahryar Zeyghami, Farzaneh Masihi

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Golnar SabetianTrauma Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Farid ZandAnaesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Elham AsadpourAnaesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. asadpoure@sums.ac.ir.ORCID http://orcid.org/0000-0002-6858-5311
Mohammad GhorbaniTorbat Heydarieh University of Medical Sciences, Torbat Heydarieh, Iran.
Pourya AdibiAnaesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Mehdi HosseiniDepartment of Urology, Shiraz University of Medical Sciences, Shiraz, Iran.
Shahryar ZeyghamiDepartment of Urology, Shiraz University of Medical Sciences, Shiraz, Iran.
Farzaneh MasihiAnaesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences · IRTorbat Heydarieh University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransurethral resection of prostate (TURP) is the most common treatment for benign prostatic hyperplasia (BPH). Urinary tract catheter is inserted post-operatively which results in catheter-related bladder discomfort (CRBD) in many patients. The purpose of this study was to assess the preventive effect of hyoscine N-butyl bromide on CRBD caused by a urinary tract catheter after TURP surgery in patients with BPH.

methodsTwenty-four and twenty-six patients in the treatment and control groups were enrolled, respectively. At the end of the surgery, slow intravenous injection of 20 mg hyoscine N-butyl bromide was administered to the patients of treatment group. The severity of CRBD was followed up at five different time periods and up to 2 h after surgery.

resultsOn arrival to PACU and after 30 min of injection, statistically significant less CRBD was seen in the treatment group comparing to the control group (P ≤ 0.05 and P ≤ 0.007). The total utilized meperidine dose during PACU stay and the time to discharge for the intervention group were significantly lower than those for the control group (P ≤ 0.0001) with no significant difference in adverse effects (P > 0.05).

conclusionsHyoscine N-butyl bromide could reduce the severity of CRBD related to TURP in patients with BPH and their need for analgesic consumption either. It shortened the length of stay in the recovery room. Regarding its availability and low cost, it can be an effective pain relief drug for CRBD discomfort related to TURP in BPH patients.

Indexed as

AgedAnalgesics, OpioidButylscopolammonium BromideCatheters, IndwellingDouble-Blind MethodHumansMaleMeperidineMiddle AgedPain MeasurementParasympatholyticsPostoperative PainProstatic HyperplasiaTransurethral Resection of ProstateUrinary CathetersAnalgesics, OpioidButylscopolammonium BromideMeperidineParasympatholyticsBenign prostatic hyperplasiaButylscopolammonium bromideCatheter-related bladder discomfortTransurethral prostate resection

Identifiers

PMID28808847
OpenAlexW2749740198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.