Evidence map›Paper›PMID 28808772›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2018

Longitudinal strain assessed by cardiac magnetic resonance correlates to hemodynamic findings in patients with severe aortic stenosis and predicts positive remodeling after transcatheter aortic valve replacement.

Dominik Buckert, Maciej Cieslik, Raid Tibi, Michael Radermacher, Volker Rasche, Peter Bernhardt, Vinzenz Hombach, Wolfgang Rottbauer, Jochen Wöhrle

Abstract read
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Transcatheter aortic valve replacement for pure aortic valve regurgitation: "on-label" versus "off-label" use of TAVR devices.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Pooled it
  2. Long-term effects of device-guided slow breathing in stable heart failure patients with reduced ejection fraction.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Cardiac MRI in Fabry disease.Frontiers in cardiovascular medicine · 2022
    Review
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Left ventricular geometry and function in early repolarization: results from the population-based Gutenberg Health Study.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Observational
  17. Review
  18. Test-retest reliability of new and conventional echocardiographic parameters of left ventricular systolic function.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Article
  19. Transcatheter valve-in-valve implantation (VinV-TAVR) for failed surgical aortic bioprosthetic valves.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dominik BuckertDepartment of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany. dominik.buckert@uniklinik-ulm.de.ORCID http://orcid.org/0000-0001-6190-2145
Maciej CieslikDepartment of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.
Raid TibiDepartment of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.
Michael RadermacherDepartment of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.
Volker RascheDepartment of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.
Peter BernhardtDepartment of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.
Vinzenz HombachDepartment of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.
Wolfgang RottbauerDepartment of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.
Jochen WöhrleDepartment of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo assess left-ventricular strain parameters before and after transcatheter aortic valve replacement (TAVR) by feature tracking cardiac magnetic resonance imaging (FT CMR) and to correlate the findings to hemodynamic state and left-ventricular remodeling. METHODS AND

resultsPatients with symptomatic AS underwent FT CMR before and after TAVR. Patients were carefully evaluated by a comprehensive work-up including CMR, echocardiography and left and right heart catheterization. Thirty patients formed the study population. High-flow/high-gradient (HF/HG) aortic stenosis was diagnosed in 11 patients (36.7%), 6 patients (20.0%) exhibited low-flow/low-gradient AS (LF/LG) and 13 patients (43.3%) were classified to have so-called paradoxical low-flow/low-gradient (PLF/LG) AS. The HF/HG patients had a significantly reduced longitudinal strain which recovered after TAVR (-12.67 ± 4.60 to -15.46 ± 5.61%, p = 0.048). In the LF/LG group, an even more pronounced reduction of longitudinal strain and also an impairment of longitudinal velocity could be observed. Both parameters improved after therapy (strain: -5.06 ± 4.25 to -8.02 ± 3.28%, p = 0.045; velocity: 25.33 ± 9.63 to 37.13 ± 11.64 mm/s, p = 0.042). Patients with PLF/LG showed preserved longitudinal strain but a reduction of longitudinal velocity similar to the LF/LG group. These patients did not show a significant improvement of strain parameters after TAVR. Longitudinal velocity exhibited the highest predictive power for the identification of a low-flow state (sensitivity 75%, specificity 80%).

conclusionImprovement of longitudinal strain parameters after TAVR is dependent on the initial hemodynamically defined AS subgroup.

Indexed as

HemodynamicsMagnetic Resonance Imaging, CineMyocardial ContractionTranscatheter Aortic Valve ReplacementVentricular Function, LeftVentricular RemodelingAgedAged, 80 and overAortic ValveAortic Valve StenosisBiomechanical PhenomenaContrast MediaFemaleHumansMalePredictive Value of TestsContrast MediaCardiac magnetic resonance imagingCardiac mechanicsSevere aortic stenosisStrain imagingTranscatheter aortic valve replacement

Identifiers

PMID28808772
PMCPMC5760599

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.