Evidence map›Paper›PMID 28808770›Full record

ArticleEuropean journal of nutrition2018

Associations between serum calcium, phosphorus and mortality among patients with coronary heart disease.

Qian Chen, Yuan Zhang, Ding Ding, Dan Li, Yunou Yang, Qing Li, Xuechen Chen, Gang Hu, Wenhua Ling

Open access · greenAbstract read
In one paragraph

Article in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 42 citations in OpenAlex.

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  20. Self-Care by Muslim Women during Ramadan Fasting to Protect Nutritional and Cardiovascular Health.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Qian ChenGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangdong, 510080, China.
Yuan ZhangDepartment of Cardiology, General Hospital of Guangzhou Military Command of People's Liberation Army, Guangzhou, China.
Ding DingGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangdong, 510080, China.
Dan LiGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangdong, 510080, China.
Yunou YangGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangdong, 510080, China.
Qing LiGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangdong, 510080, China.
Xuechen ChenGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangdong, 510080, China.
Gang HuChronic Disease Epidemiology Laboratory, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA, 70808, USA. gang.hu@pbrc.edu.
Wenhua LingGuangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangdong, 510080, China. lingwh@mail.sysu.edu.cn.
Sun Yat-sen University · CNPennington Biomedical Research Center · USGeneral Hospital of Guangzhou Military Command · CN

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI JUDD E SHELLITO · 2012 to 2026
$69.1M
National Natural Science Foundation of China 81130052National Natural Science Foundation of China 81402671NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

purposeSerum calcium and phosphorus abnormalities are associated with cardiovascular disorders in general population, but evidence among patients with established coronary heart disease (CHD) is limited and controversial. This study aimed to investigate the associations of baseline serum calcium and phosphorus levels with long-term mortality risk among patients with CHD.

methodsWe conducted a prospective cohort study among 3187 patients with CHD from October 2008 and December 2011 in China. Cox proportional hazards model was used to assess the associations of serum calcium and phosphorus at baseline with the risk of death.

resultsDuring follow-up (mean, 4.9 years), 295 patients died, 193 of which resulted from cardiovascular causes. Multivariable-adjusted hazard ratios (HR) for each 1 mmol/L increase in serum calcium at baseline were 0.27 (95% confidence interval (CI) 0.14-0.51) for all-cause mortality and 0.26 (95% CI 0.12-0.54) for cardiovascular mortality. Patients in the highest compared to the lowest quartile of serum calcium were at lower risk of all-cause mortality (HR, 95% CI 0.57, 0.40-0.82) and cardiovascular mortality (0.50, 0.32-0.79) (both P

conclusionsThe present study is the first to report that lower serum calcium at baseline is associated with an increased risk of all-cause and cardiovascular mortality in a Chinese coronary heart disease cohort. Further studies are required to investigate the causal relationship and actual mechanisms.

Indexed as

CalciumCardiovascular DiseasesChinaCoronary DiseaseHumansPhosphorusProportional Hazards ModelsProspective StudiesRisk FactorsCalciumPhosphorusCardiovascular diseaseCohort studyMineral metabolismMortality

Identifiers

PMID28808770
PMCPMC9048852
OpenAlexW2747627340

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.