ArticleBioMed research international2017
Effect of Pregnancy on Quantitative Medication Use and Relation to Exacerbations in Asthma.
Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- The nationwide retrospective cohort study by Health Insurance Review and Assessment Service proves that asthma management decreases the exacerbation risk of asthma.Scientific reports · 2021Trial
- Inhaled Corticosteroids Continuation in the First Trimester and Pregnancy Outcomes in Women With Asthma.JAMA network open · 2026Article
- Asthma Medication Adherence and Exacerbations in Pregnancy: Bridging the Gap Between Evidence and Practice.Allergy, asthma & immunology research · 2026Article
- How Pregnancy Affects Asthma in Korea: Risk Factors and Adherence Decline.Allergy, asthma & immunology research · 2026Article
- Asthma Exacerbation Risk in Pregnancy and Postpartum: Assessing the Impact of Gestational Diabetes Mellitus and Other Key Factors.The journal of allergy and clinical immunology. In practice · 2025Article
- Asthma in pregnancy.Allergy and asthma proceedings · 2023Review
- An update on the physiologic changes during pregnancy and their impact on drug pharmacokinetics and pharmacogenomics.Journal of basic and clinical physiology and pharmacology · 2022Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe quantification of asthma medication reduction and its relation to an aggravation of asthma during pregnancy at an individual level are unclear.
methodsWe conducted a nationwide retrospective cohort study of asthmatic pregnant women in South Korea. All of the asthma medications were ranked from 1 to 4 according to the guideline-based stepwise approach. We assessed the daily sums of the ranks of the asthma medications and their association with exacerbations during three phases based on the individual's delivery date: before, during, and after pregnancy.
resultsThe study cohort included 115,169 asthmatic pregnant women who gave birth between 2011 and 2013. The subjects were clustered into four groups according to the daily rank sums of their asthma medication. Asthma medications were rapidly reduced at the beginning of the pregnancy and then slowly increased after delivery. Exacerbations were more frequent in the group with higher rank-sum values than in the group with lower values. Overall exacerbations were reduced during pregnancy compared to before or after delivery.
conclusionsAsthmatic pregnant women tended to reduce their asthma medication use during pregnancy. This led to a greater number of exacerbations in a small part of the study population.
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