ArticleChemical science2016
Length-independent transport rates in biomolecules by quantum mechanical unfurling.
Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed.
- From single step hops to emergent biological phenomena.Journal of inorganic biochemistry · 2026Review
- Hole Transfer and the Resulting DNA Damage.Biomolecules · 2024Review
- Modeling Charge Transfer Reactions by Hopping between Electronic Ground State Minima: Application to Hole Transfer between DNA Bases.Molecules (Basel, Switzerland) · 2022Article
- Electron Transfer Rates in Polar and Non-Polar Environments: a Generalization of Marcus' Theory to Include an Effective Treatment of Tunneling Effects.The journal of physical chemistry letters · 2022Article
- The Time Scale of Electronic Resonance in Oxidized DNA as Modulated by Solvent Response: An MD/QM-MM Study.Molecules (Basel, Switzerland) · 2021Article
- Coherent Effects in Charge Transport in Molecular Wires: Toward a Unifying Picture of Long-Range Hole Transfer in DNA.The journal of physical chemistry letters · 2020Article
- The Dynamics of Hole Transfer in DNA.Molecules (Basel, Switzerland) · 2019Review
- Why Are DNA and Protein Electron Transfer So Different?Annual review of physical chemistry · 2019Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Experiments on hole transfer in DNA between donor and acceptor moieties revealed transfer rates which are independent of the molecular bridge length (within experimental error). However, the physical origin of this intriguing observation is still unclear. The hopping model implies that the hole propagates in multiple steps along the bridge from one localized state to another, and therefore the longer the bridge, the slower the transfer. This can explain weak length-dependence but not a length-independent transfer rate. We show that the rigid molecular structure of a poly-A bridge supports single step transitions from a localized hole state to delocalized states, spread over the entire bridge. Since propagation to the bridge end is a single step process (termed quantum unfurling) the transfer rate becomes independent of the bridge length. This explanation is consistent with experimental results, and emphasizes the importance of structural order in charge transfer through bio-molecular systems.
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Registered trials
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