Evidence map›Paper›PMID 28808503›Full record

ArticleWorld journal of gastrointestinal oncology2017

Prognostic efficacy of inflammation-based markers in patients with curative colorectal cancer resection.

Özgür Akgül, Erdinç Çetinkaya, Metin Yalaza, Sabri Özden, Mesut Tez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Özgür AkgülÖzgür Akgül, Erdinç Çetinkaya, Metin Yalaza, Sabri Özden, Mesut Tez, General Surgery Department, Ankara Numune Training and Research Hospital, 06100 Ankara, Turkey.
Erdinç ÇetinkayaÖzgür Akgül, Erdinç Çetinkaya, Metin Yalaza, Sabri Özden, Mesut Tez, General Surgery Department, Ankara Numune Training and Research Hospital, 06100 Ankara, Turkey.
Metin YalazaÖzgür Akgül, Erdinç Çetinkaya, Metin Yalaza, Sabri Özden, Mesut Tez, General Surgery Department, Ankara Numune Training and Research Hospital, 06100 Ankara, Turkey.
Sabri ÖzdenÖzgür Akgül, Erdinç Çetinkaya, Metin Yalaza, Sabri Özden, Mesut Tez, General Surgery Department, Ankara Numune Training and Research Hospital, 06100 Ankara, Turkey.
Mesut TezÖzgür Akgül, Erdinç Çetinkaya, Metin Yalaza, Sabri Özden, Mesut Tez, General Surgery Department, Ankara Numune Training and Research Hospital, 06100 Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the prognostic significance of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and prognostic nutritional index (PNI) and other clinicopathological factors in patients undergoing curative resection of colon cancer.

methods183 patients with histologically proven colorectal cancer who had undergone potentially curative resection between 2010 and 2016 at Ankara Numune Training and Research Hospital were retrospectively analyzed and clinicopathological characteristics included age, sex, tumor type, grade, size and localization, the number of metastatic and total number of lymph nodes removed, vascular and perineural invasion of the tumor, TNM stages, tumor marker levels (CEA, CA19-9, AFP, CA-125, CA15-3), complete blood counts, albumin levels, overall survival (months), NLR, PLR, LMR and PNI ratios were retrospectively reviewed and analyzed from the electronic database. The primary outcome measure was overall survival.

resultsRegarding overall survival, on univariate analysis the following variables were significantly associated with poor outcome following resection: T-stage (

conclusionThis study shows that decrease in the PNI and increase in CA 19-9 is associated with poor survival in patients with resectable colon cancer.

Indexed as

CA19-9Colorectal cancerOverall survivalPrognosisPrognostic nutritional index

Identifiers

PMID28808503
PMCPMC5534398

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.