Evidence map›Paper›PMID 28808477›Full record

ArticleAnnals of general psychiatry2017

Effect of lamotrigine in the treatment of bipolar depression with psychotic features: a case report.

Tomoko Kajiya, Hiroko Sugawara, Yusuke Kajio, Satoru Morieda, Hibiki Tanaka, Tadashi Jono, Noboru Fujise, Mamoru Hashimoto

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of general psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tomoko KajiyaDepartment of Neuropsychiatry, Faculty of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto 860-8556 Japan.
Hiroko SugawaraDepartment of Neuropsychiatry, Faculty of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto 860-8556 Japan.
Yusuke KajioDepartment of Neuropsychiatry, Faculty of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto 860-8556 Japan.
Satoru MoriedaDepartment of Neuropsychiatry, Faculty of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto 860-8556 Japan.
Hibiki TanakaDepartment of Neuropsychiatry, Faculty of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto 860-8556 Japan.
Tadashi JonoDepartment of Neuropsychiatry, Faculty of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto 860-8556 Japan.
Noboru FujiseKumamoto University Healthcare Center, Kumamoto, Japan.
Mamoru HashimotoDepartment of Neuropsychiatry, Faculty of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto-Shi, Kumamoto 860-8556 Japan.
Kumamoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMajor depressive episodes with psychotic features are more common in bipolar disorder than in major depressive disorder; however, there is little information on the optimal treatment for bipolar depression with psychotic features. CASE PRESENTATION: The patient was a 69-year-old man. At the age of 66, he was admitted to the hospital for the treatment of bipolar depression with psychotic features. He was treated with a combination therapy of antipsychotics and antidepressants during long-term hospitalization. At the age of 69, he relapsed and was admitted to the hospital again. He was initially treated with olanzapine and lithium for the treatment of bipolar depression with psychotic features. He partially responded to the combination therapy, and psychomotor retardation and delusion of guilt disappeared; however, he developed psychomotor agitation and delusion of persecution, which was a mood-incongruent psychotic feature. Finally, he fully recovered with an additional dosage of lamotrigine, and had no experience of relapse after discontinuation of olanzapine.

conclusionsThis case report implicates the utility of lamotrigine for bipolar depression with psychotic features, and further studies are needed to establish the optimal treatment.

Indexed as

Bipolar depressionGlutamatergic functionLamotrigineMood-incongruentPsychotic features

Identifiers

PMID28808477
PMCPMC5551021
OpenAlexW2744947100

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.