Evidence map›Paper›PMID 28808424›Full record

ArticleInternational journal of biological sciences2017

Acetylation of hMOF Modulates H4K16ac to Regulate DNA Repair Genes in Response to Oxidative Stress.

Jianing Zhong, Liying Ji, Huiqian Chen, Xianfeng Li, Jian'an Zhang, Xingxing Wang, Weilin Wu, Ying Xu, Fei Huang, Wanshi Cai and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jianing ZhongThe Science Research Center, Gannan Medical University, Ganzhou 341000, China.
Liying JiInstitute of Genomic Medicine, Wenzhou Medical University, Wenzhou 325035, China.
Huiqian ChenInstitute of Genomic Medicine, Wenzhou Medical University, Wenzhou 325035, China.
Xianfeng LiBeijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China.
Jian'an ZhangInstitute of Genomic Medicine, Wenzhou Medical University, Wenzhou 325035, China.
Xingxing WangInstitute of Genomic Medicine, Wenzhou Medical University, Wenzhou 325035, China.
Weilin WuThe Science Research Center, Gannan Medical University, Ganzhou 341000, China.
Ying XuThe Science Research Center, Gannan Medical University, Ganzhou 341000, China.
Fei HuangThe Science Research Center, Gannan Medical University, Ganzhou 341000, China.
Wanshi CaiBeijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China.
Zhong Sheng SunInstitute of Genomic Medicine, Wenzhou Medical University, Wenzhou 325035, China.
Wenzhou Medical University · CNChinese Nutrition Society · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress is considered to be a key risk state for a variety of human diseases. In response to oxidative stress, the regulation of transcriptional expression of DNA repair genes would be important to DNA repair and genomic stability. However, the overall pattern of transcriptional expression of DNA repair genes and the underlying molecular response mechanism to oxidative stress remain unclear. Here, by employing colorectal cancer cell lines following exposure to hydrogen peroxide, we generated expression profiles of DNA repair genes

Indexed as

DNA RepairColorectal NeoplasmsGene Expression RegulationHCT116 CellsHistone AcetyltransferasesHistonesHumansHydrogen PeroxideNucleic Acid Amplification TechniquesOxidative StressPromoter Regions, GeneticRNASirtuin 1Histone AcetyltransferasesHistonesHydrogen PeroxideKAT8 protein, humanRNASIRT1 protein, humanSirtuin 1H4K16achMOFOxidative Stress

Identifiers

PMID28808424
PMCPMC5555109
OpenAlexW2741100414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.