ArticleScientific reports2017
Milk microbiome and bacterial load following dry cow therapy without antibiotics in dairy cows with healthy mammary gland.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 94 citations in OpenAlex.
- Variations in cow milk and teat skin microbiota across the lactation cycle with intramammary cephalosporin use at dry-off.Applied and environmental microbiology · 2026Article
- Longitudinal study of mammary microbiota dynamics and mastitis prevention in Holstein cows by dry-off strategy.Frontiers in veterinary science · 2026Article
- The Microbial Composition of Bovine Colostrum as Influenced by Antibiotic Treatment.Antibiotics (Basel, Switzerland) · 2025Article
- Effect of probiotic Lactobacillus plantarum CM49 on microbial profile and lactobacilli counts in milk of mastitic cattle.BMC microbiology · 2025Article
- Use of approved cefazolin based intramammary dry goat treatment and its effects on the milk microbiota.Scientific reports · 2025Article
- Modified Huangqi Shengmai Yin enhances ruminal microbiome and metabolites activity in dairy cows with subclinical mastitis.Frontiers in veterinary science · 2025Article
- Resistome and microbiome profiling of bovine milk following antimicrobial dry cow therapy: insights from short- and long-read metagenomic sequencing.Frontiers in microbiomes · 2025Article
- The occurrence ofmSystems · 2024Article
- Vertical transfer of gut microbiota from dam to neonate calf in the early of life.Scientific reports · 2024Article
- Aloe arborescens supplementation in drying-off dairy cows: influence on rumen, rectum and milk microbiomes.Animal microbiome · 2024Article
- Revealing microbial diversity in buffalo milk with high somatic cell counts: implications for mastitis diagnosis and treatment.Veterinary research communications · 2024Article
- Bovine milk microbiota: Key players, origins, and potential contributions to early-life gut development.Journal of advanced research · 2024Review
- Microbiological risk assessment and resistome analysis from shotgun metagenomics of bovine colostrum microbiome.Saudi journal of biological sciences · 2024Article
- Staphylococcal mastitis in dairy cows.Frontiers in veterinary science · 2024Review
- Persistent effects of intramammary ceftiofur treatment on the gut microbiome and antibiotic resistance in dairy cattle.Animal microbiome · 2023Article
- Microbiota and Resistome Analysis of Colostrum and Milk from Dairy Cows Treated with and without Dry Cow Therapies.Antibiotics (Basel, Switzerland) · 2023Article
- Effect of the Selective Dry Cow Therapy on Udder Health and Milk Microbiota.Antibiotics (Basel, Switzerland) · 2023Article
- Bovine Udder Health: From Standard Diagnostic Methods to New Approaches-A Practical Investigation of Various Udder Health Parameters in Combination with 16S rRNA Sequencing.Microorganisms · 2023Article
- Effects of Intramammary Antimicrobial Treatment on the Milk Microbiota Composition in Mild Clinical Bovine Mastitis Caused by Gram-Positive Bacteria.Animals : an open access journal from MDPI · 2023Article
- Changes in bovine milk bacterial microbiome from healthy and subclinical mastitis affected animals of the Girolando, Gyr, Guzera, and Holstein breeds.International microbiology : the official journal of the Spanish Society for Microbiology · 2022Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preventive infusion of antibiotics in the mammary gland of cows consumes 11 tons/year of medically relevant antimicrobials, yet, this practice might not be critical to prevent new infections in the healthy mammary gland of cows. Here, we used next-generation sequencing and quantitative real-time PCR to determine the impact of dry cow therapy without antibiotics on milk microbiome and bacterial load, respectively. Cows diagnosed as negative for mastitis at dry off were randomly allocated to receive antibiotic (intramammary ceftiofur hydrochloride) and teat sealant or just teat sealant. Firmicutes was the most abundant phylum, and Corynebacterium, Acinetobacter, and Staphylococcus, often involved in mastitis cases, were the most abundant genera across treatments and time. However, there were no effects of antimicrobial on milk microbiome and bacterial load. Bacterial load was greater at seven days postpartum than at dry off. Dry cow therapy based on teat sealant without antibiotics can be used with no detrimental impacts on milk microbiome and bacterial load in cows with a healthy mammary gland.
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