Evidence map›Paper›PMID 28808163›Full record

ArticleInfection and immunity2017

Role for FimH in Extraintestinal Pathogenic Escherichia coli Invasion and Translocation through the Intestinal Epithelium.

Nina M Poole, Sabrina I Green, Anubama Rajan, Luz E Vela, Xi-Lei Zeng, Mary K Estes, Anthony W Maresso

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Is Virulence GeneInfectious disease reports · 2026
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  3. Review
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  5. Article
  6. Review
  7. Article
  8. Article
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  10. Review
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  12. Article
  13. Article
  14. Article
  15. Genome characterization of a multi-drug resistantFrontiers in microbiology · 2024
    Article
  16. Article
  17. Comprehensive Analysis of Virulence Genes, Antibiotic Resistance, Biofilm Formation, and Sequence Types in Clinical Isolates ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Article
  18. Review
  19. Frontiers in immunology · 2023
    Article
  20. Survival and Virulence Potential of Drug-ResistantInternational journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nina M PooleDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Sabrina I GreenDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Anubama RajanDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Luz E VelaDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Xi-Lei ZengDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Mary K EstesDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Anthony W MaressoDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA maresso@bcm.edu.
Baylor College of Medicine · US

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Hashem B El-Serag · 2001 to 2026
$28.3M
Novel Platforms for Human Intestinal Enteroids: Matrix, Mechanics, and TopographyU19AI116497 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI GRANDE-ALLEN, KATHRYN JANE · 2015 to 2025
$13.2M
Initiative for Maximizing Student Development (IMSD) ProgramR25GM056929 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI PEREIRA, FRED A · 1998 to 2023
$12.4M
Research Education and Career Horizons ProgramK12GM084897 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI SIFERS, RICHARD NORMAN, SLAUGHTER, GAYLE · 2008 to 2016
$8.3M
Research Training in Infections and ImmunityT32AI055413 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI GIORDANO, THOMAS P, MYSOREKAR, INDIRA U · 2003 to 2024
$3.2M
Branched Chain Amino Acid Metabolism During AnthraxR21AI146481 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI MARESSO, ANTHONY W · 2019 to 2020
$440k
The Role of FimH in ExPEC TranslocationR21AI126354 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI MARESSO, ANTHONY W · 2016 to 2017
$436k
NIAID NIH HHS R21 AI126354NIAID NIH HHS R21 AI146481NIAID NIH HHS T32 AI055413NIAID NIH HHS U19 AI116497NIDDK NIH HHS P30 DK056338NIGMS NIH HHS K12 GM084897NIGMS NIH HHS R25 GM056929
6 · The paper itself

Abstract

The translocation of bacteria across the intestinal epithelium of immunocompromised patients can lead to bacteremia and life-threatening sepsis. Extraintestinal pathogenic

Indexed as

Adhesins, Escherichia coliAnimalsBacterial TranslocationCaco-2 CellsEpithelial CellsEscherichia coli InfectionsExtraintestinal Pathogenic Escherichia coliFemaleFimbriae, BacterialFimbriae ProteinsGene ExpressionHumansJejunumKidneyLungMaleAdhesins, Escherichia coliFimbriae ProteinsfimH protein, E coliExPECFimHintestinal epitheliuminvasiontranslocation

Identifiers

PMID28808163
PMCPMC5649017
OpenAlexW2747943352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.