Evidence map›Paper›PMID 28808160›Full record

ArticleInfection and immunity2017

Incremental Contributions of FbaA and Other Impetigo-Associated Surface Proteins to Fitness and Virulence of a Classical Group A Streptococcal Skin Strain.

Candace N Rouchon, Anhphan T Ly, John P Noto, Feng Luo, Sergio Lizano, Debra E Bessen

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Interplay between group AMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  3. Review
  4. Article
  5. Article
  6. Case Report: Septic arthritis in children caused byFrontiers in cellular and infection microbiology · 2022
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Candace N RouchonDepartment of Microbiology and Immunology, New York Medical College, Valhalla, New York, USA.
Anhphan T LyDepartment of Microbiology and Immunology, New York Medical College, Valhalla, New York, USA.
John P NotoDepartment of Microbiology and Immunology, New York Medical College, Valhalla, New York, USA.
Feng LuoDepartment of Microbiology and Immunology, New York Medical College, Valhalla, New York, USA.
Sergio LizanoDepartment of Microbiology and Immunology, New York Medical College, Valhalla, New York, USA.
Debra E BessenDepartment of Microbiology and Immunology, New York Medical College, Valhalla, New York, USA debra_bessen@nymc.edu.
New York Medical College · US

Funding

Population genomics of Streptococcus pyogenesR01AI065572 · NIAID · NEW YORK MEDICAL COLLEGE · PI BESSEN, DEBRA E · 2005 to 2009
$1.8M
Tissue-Specific Infection by Group A StreptococciR01AI053826 · NIAID · NEW YORK MEDICAL COLLEGE · PI BESSEN, DEBRA E · 2003 to 2007
$1.3M
Tissue-Specific Infection by Group A StreptococciR56AI053826 · NIAID · NEW YORK MEDICAL COLLEGE · PI BESSEN, DEBRA E · 2008 to 2009
$808k
NIAID NIH HHS R01 AI053826NIAID NIH HHS R01 AI065572NIAID NIH HHS R56 AI053826
6 · The paper itself

Abstract

Group A streptococci (GAS) are highly prevalent human pathogens whose primary ecological niche is the superficial epithelial layers of the throat and/or skin. Many GAS strains with a strong tendency to cause pharyngitis are distinct from strains that tend to cause impetigo; thus, genetic differences between them may confer host tissue-specific virulence. In this study, the FbaA surface protein gene was found to be present in most skin specialist strains but largely absent from a genetically related subset of pharyngitis isolates. In an Δ

Indexed as

Gene Expression Regulation, BacterialAnimalsBacterial ProteinsBlood CellsCarrier ProteinsDisease Models, AnimalFructose-Bisphosphate AldolaseGenetic FitnessHost-Pathogen InteractionsHumansImpetigoMicePharyngitisPharynxProtein IsoformsSkinBacterial ProteinsCarrier ProteinsFba protein, Streptococcus pyogenesFructose-Bisphosphate Aldolaseplasminogen-binding protein, bacteriaProtein Isoformsgroup A streptococciimpetigophagocytosisStreptococcus pyogenessurface proteins

Identifiers

PMID28808160
PMCPMC5649008
OpenAlexW2745588926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.