Evidence map›Paper›PMID 28808159›Full record

ArticleInfection and immunity2017

Chronic Brucella Infection Induces Selective and Persistent Interferon Gamma-Dependent Alterations of Marginal Zone Macrophages in the Spleen.

Arnaud Machelart, Abir Khadrawi, Aurore Demars, Kevin Willemart, Carl De Trez, Jean-Jacques Letesson, Eric Muraille

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. A Putative Multicopper Oxidase Encoded byInternational journal of molecular sciences · 2026
    Article
  2. OralFrontiers in microbiology · 2026
    Article
  3. Exploring CD169Vaccines · 2025
    Review
  4. Review
  5. Article
  6. The Role of Neutrophils in Brucellosis.Microbiology and molecular biology reviews : MMBR · 2020
    Review
  7. Article
  8. Interaction betweenJournal of veterinary science · 2019
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Arnaud MachelartUnité de Recherche en Biologie des Microorganismes, Laboratoire d'Immunologie et de Microbiologie, Université de Namur, Namur, Belgium.
Abir KhadrawiUnité de Recherche en Biologie des Microorganismes, Laboratoire d'Immunologie et de Microbiologie, Université de Namur, Namur, Belgium.
Aurore DemarsUnité de Recherche en Biologie des Microorganismes, Laboratoire d'Immunologie et de Microbiologie, Université de Namur, Namur, Belgium.
Kevin WillemartUnité de Recherche en Biologie des Microorganismes, Laboratoire d'Immunologie et de Microbiologie, Université de Namur, Namur, Belgium.
Carl De TrezResearch Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel and Vlaams Instituut voor Biotechnologie, Department of Structural Biology Research Center, Brussels, Belgium.
Jean-Jacques LetessonUnité de Recherche en Biologie des Microorganismes, Laboratoire d'Immunologie et de Microbiologie, Université de Namur, Namur, Belgium.
Eric MurailleLaboratoire de Parasitologie, Université Libre de Bruxelles, Brussels, Belgium emuraille@hotmail.com.
University of Namur · BEUniversité Libre de Bruxelles · BEVrije Universiteit Brussel · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spleen is known as an important filter for blood-borne pathogens that are trapped by specialized macrophages in the marginal zone (MZ): the CD209

Indexed as

Host-Pathogen InteractionsAnimalsAnti-Bacterial AgentsB-LymphocytesBrucella abortusBrucella melitensisBrucella suisBrucellosisChemokine CCL19Chemokine CCL21Chemokine CXCL13Chronic DiseaseGene Expression RegulationInterferon-gammaInterferon gamma ReceptorMacrophagesAnti-Bacterial AgentsCcl19 protein, mouseChemokine CCL19Chemokine CCL21Chemokine CXCL13Cxcl13 protein, mouseInterferon-gammaInterferon gamma ReceptorReceptors, InterferonReceptors, Tumor Necrosis Factor, Type IRifampinRNA, MessengerStreptomycinBrucella melitensisbrucellosisinfectionlow-grade Th1 inflammationmarginal zone macrophagesspleen

Identifiers

PMID28808159
PMCPMC5649024
OpenAlexW2747233922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.