Evidence map›Paper›PMID 28808137›Full record

ArticleBiology open2017

Regulatory RNPs: a novel class of ribonucleoproteins that potentially contribute to ribosome heterogeneity.

Aaron R Poole, Ian Vicino, Hironori Adachi, Yi-Tao Yu, Michael D Hebert

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. A Novel Role for Coilin in Vertebrate Innate Immunity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
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  12. Alteration of 28S rRNA 2'-Biology open · 2019
    Article
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  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aaron R PooleDepartment of Biochemistry, The University of Mississippi Medical Center, Jackson, MS 39216-4505, USA.
Ian VicinoDepartment of Biochemistry, The University of Mississippi Medical Center, Jackson, MS 39216-4505, USA.
Hironori AdachiDepartment of Biochemistry and Biophysics, The University of Rochester Medical Center, Rochester, NY 14642, USA.
Yi-Tao YuDepartment of Biochemistry and Biophysics, The University of Rochester Medical Center, Rochester, NY 14642, USA.
Michael D HebertDepartment of Biochemistry, The University of Mississippi Medical Center, Jackson, MS 39216-4505, USA mhebert@umc.edu.ORCID http://orcid.org/0000-0002-6233-9654
Jackson Memorial Hospital · USUniversity of Rochester Medical Center · US

Funding

Expanding the genetic code by targeted pseudouridylationR01GM104077 · NIGMS · UNIVERSITY OF ROCHESTER · PI YU, YI-TAO · 2012 to 2015
$1.2M
NIGMS NIH HHS R01 GM104077
6 · The paper itself

Abstract

Many ribonucleoproteins (RNPs), which are comprised of noncoding RNA and associated proteins, are involved in essential cellular processes such as translation and pre-mRNA splicing. One class of RNP is the small Cajal body-specific RNP (scaRNP), which contributes to the biogenesis of small nuclear RNPs (snRNPs) that are central components of the spliceosome. Three scaRNAs are internally processed, generating stable nucleolus-enriched RNAs of unknown function. Here, we provide data that show that these RNAs become part of RNPs we term regulatory RNPs (regRNPs). Most modifications within rRNA (predominantly pseudouridylation and ribose 2'-

Indexed as

Cajal bodyMethylationNucleolusScaRNASnoRNP

Identifiers

PMID28808137
PMCPMC5612246
OpenAlexW2746276076

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.