Evidence map›Paper›PMID 28808038›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

The Phosphatidylinositol 3-Kinase Pathway as a Potential Therapeutic Target in Bladder Cancer.

Shu-Xiong Zeng, Yanjun Zhu, Ai-Hong Ma, Weimin Yu, Hongyong Zhang, Tzu-Yin Lin, Wei Shi, Clifford G Tepper, Paul T Henderson, Susan Airhart and 4 more

Open access · greenAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 60 citations in OpenAlex.

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  10. Landscape of targeted therapies for advanced urothelial carcinoma.Exploration of targeted anti-tumor therapy · 2024
    Review
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  12. Review
  13. Article
  14. Phototherapy with Cancer-Specific Nanoporphyrin Potentiates Immunotherapy in Bladder Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
    Article
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Shu-Xiong ZengDivision of Hematology and Oncology, Department of Internal Medicine, School of Medicine, University of California Davis, Sacramento, California.
Yanjun ZhuDivision of Hematology and Oncology, Department of Internal Medicine, School of Medicine, University of California Davis, Sacramento, California.
Ai-Hong MaDepartment of Biochemistry and Molecular Medicine, School of Medicine, University of California Davis, Sacramento, California.
Weimin YuDivision of Hematology and Oncology, Department of Internal Medicine, School of Medicine, University of California Davis, Sacramento, California.
Hongyong ZhangDivision of Hematology and Oncology, Department of Internal Medicine, School of Medicine, University of California Davis, Sacramento, California.
Tzu-Yin LinDivision of Hematology and Oncology, Department of Internal Medicine, School of Medicine, University of California Davis, Sacramento, California.
Wei ShiDivision of Hematology and Oncology, Department of Internal Medicine, School of Medicine, University of California Davis, Sacramento, California.
Clifford G TepperDepartment of Biochemistry and Molecular Medicine, School of Medicine, University of California Davis, Sacramento, California.
Paul T HendersonDivision of Hematology and Oncology, Department of Internal Medicine, School of Medicine, University of California Davis, Sacramento, California.
Susan AirhartThe Jackson Laboratory, Bar Harbor, Maine.
Jian-Ming GuoDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Chuan-Liang XuDepartment of Urology, Changhai Hospital, Second Military Medical University, Shanghai, China. cxpan@ucdavis.edu xuchuanliang@vip.126.com.
Ralph W deVere WhiteDepartment of Urology, University of California Davis Comprehensive Cancer Center, Sacramento, California.
Chong-Xian PanDivision of Hematology and Oncology, Department of Internal Medicine, School of Medicine, University of California Davis, Sacramento, California. cxpan@ucdavis.edu xuchuanliang@vip.126.com.
University of California, Davis · USFudan University · CNSecond Military Medical University · CNJackson Laboratory · USUniversity of California Davis Medical Center · USVA Northern California Health Care System · USWuhan University · CNXijing Hospital · CN

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Laura Marcu · 2002 to 2026
$84.9M
Development of targeting nanotherapeutics against bladder cancerI01BX001784 · VA · VA NORTHERN CALIFORNIA HEALTH CARE SYS · PI PAN, CHONG-XIAN · 2014 to 2017
–
BLRD VA I01 BX001784NCI NIH HHS P30 CA093373
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Line, TumorCisplatinClass I Phosphatidylinositol 3-KinasesDeoxycytidineDrug Resistance, NeoplasmGemcitabineGene Expression Regulation, NeoplasticHumansIndazolesMiceMutationPhosphatidylinositol 3-KinaseProtein Kinase InhibitorsSignal TransductionSulfonamides2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidineCisplatinClass I Phosphatidylinositol 3-KinasesDeoxycytidineGemcitabineIndazolesPhosphatidylinositol 3-KinasePIK3CA protein, humanProtein Kinase InhibitorsSulfonamides

Identifiers

PMID28808038
PMCPMC5668181
OpenAlexW2750320760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.