ArticlePlant physiology2017
Identification of Novel Growth Regulators in Plant Populations Expressing Random Peptides.
Article in Plant physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- A Reassessment of Positive Growth Effects of Expressed Random Sequence Clones in E. coli Suggests Direct Adaptive Functions.Genome biology and evolution · 2026Article
- Aptamers as emerging tools for plant disease management: From biosensing to active modulation.iScience · 2025Review
- Expression of Random Sequences and de novo Evolved Genes From the Mouse in Human Cells Reveals Functional Diversity and Specificity.Genome biology and evolution · 2024Article
- Experimental Evaluation of a Direct Fitness Effect of the De Novo Evolved Mouse Gene Pldi.Genome biology and evolution · 2024Article
- Hormonal Regulation and Transcriptomic Insights into Flower Development inPlants (Basel, Switzerland) · 2024Article
- The Origins and Functions of De Novo Genes: Against All Odds?Journal of molecular evolution · 2022Review
- Foster thy young: enhanced prediction of orphan genes in assembled genomes.Nucleic acids research · 2022Article
- Development of chloroplast transformation and gene expression regulation technology in land plants.Frontiers in plant science · 2022Review
- The Effects of Sequence Length and Composition of Random Sequence Peptides on the Growth ofGenes · 2021Article
- A vast pool of lineage-specific microproteins encoded by long non-coding RNAs in plants.Nucleic acids research · 2021Article
- Application of Synthetic Peptide CEP1 Increases Nutrient Uptake Rates Along Plant Roots.Frontiers in plant science · 2021Article
- Evolution of a New Testis-Specific Functional Promoter Within the Highly ConservedFrontiers in genetics · 2021Article
- Landscape of the Dark Transcriptome Revealed Through Re-mining Massive RNA-Seq Data.Frontiers in genetics · 2021Article
- Primary transcript of miR858 encodes regulatory peptide and controls flavonoid biosynthesis and development in Arabidopsis.Nature plants · 2020Article
- A synthetic peptide encoded by a random DNA sequence inhibits discrete red light responses.Plant direct · 2019Article
- fagin: synteny-based phylostratigraphy and finer classification of young genes.BMC bioinformatics · 2019Article
- Article
- Genome-Wide Identification ofPlant physiology · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of chemical genomics approaches allows the identification of small molecules that integrate into biological systems, thereby changing discrete processes that influence growth, development, or metabolism. Libraries of chemicals are applied to living systems, and changes in phenotype are observed, potentially leading to the identification of new growth regulators. This work describes an approach that is the nexus of chemical genomics and synthetic biology. Here, each plant in an extensive population synthesizes a unique small peptide arising from a transgene composed of a randomized nucleic acid sequence core flanked by translational start, stop, and cysteine-encoding (for disulfide cyclization) sequences. Ten and 16 amino acid sequences, bearing a core of six and 12 random amino acids, have been synthesized in Arabidopsis (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.