Evidence map›Paper›PMID 28807919›Full record

ArticleAntimicrobial agents and chemotherapy2017

Drug Susceptibility and Replicative Capacity of Multidrug-Resistant Recombinant Human Cytomegalovirus Harboring Mutations in

Jocelyne Piret, Nathalie Goyette, Guy Boivin

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jocelyne PiretResearch Center in Infectious Diseases, CHU of Quebec and Laval University, Quebec City, Quebec, Canada.
Nathalie GoyetteResearch Center in Infectious Diseases, CHU of Quebec and Laval University, Quebec City, Quebec, Canada.
Guy BoivinResearch Center in Infectious Diseases, CHU of Quebec and Laval University, Quebec City, Quebec, Canada guy.boivin@crchudequebec.ulaval.ca.
Université Laval · CA

Funding

CIHR 148361
6 · The paper itself

Abstract

Letermovir is an investigational antiviral agent with a novel mechanism of action involving the viral terminase (pUL56). We evaluated the impact of the V236M mutation in the

Indexed as

Antiviral AgentsCytomegalovirusCytomegalovirus InfectionsDNA-Directed DNA PolymeraseDNA ReplicationDrug Resistance, Multiple, ViralFibroblastsHumansMutationViral ProteinsViral Structural ProteinsAntiviral AgentsDNA-Directed DNA PolymeraseUL54 protein, Human herpesvirus 5UL56 protein, cytomegalovirusViral ProteinsViral Structural Proteinsantiviral agentscytomegalovirusresistance

Identifiers

PMID28807919
PMCPMC5655094
OpenAlexW2746692142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.