ArticleAntimicrobial agents and chemotherapy2017
Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection.
Erratum issued 2 registry-linked trialsAbstract readCase Reports
In one paragraph
Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 719 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
719citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Phase 1, Open-label, Randomized, Pilot and Feasibility Trial to Evaluate the Safety and Tolerability of the Achromobacter-targeting Bacteriophage Cocktail, AchromoPhage, Among Persons With Cystic Fibrosis and Chronic Achromobacter Lung Infections: The AchromoPhage Trial
NCT07619924 early_phase1enrolling by invitationnot on this mapstarted 2025, after this paper: background citation
Randomized Controlled Study on the Safety and Efficacy of Phage Cocktail in the Treatment of Multidrug-Resistant Bacterial Skin Infections
Who cites it
719 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Precision phage therapy in the AI/ML era: a systematic review of discovery-to-clinical translation evidence.Frontiers in microbiology · 2026Pooled it
- Evolutionary dynamics and research hotspots of phage applications againstFrontiers in microbiology · 2025Pooled it
- Phenotypic heterogeneity and genetic mechanisms of phage resistance in hypervirulent carbapenem-resistantVirulence · 2026Article
- Antibiotic-induced cellular enlargement drives phage synergy and resensitizes carbapenem-resistantMicrobiology spectrum · 2026Article
- Gut microbiome dynamics in acute infectious diarrhea: A conceptual framework from acute dysbiosis toward precision restoration (Review).Experimental and therapeutic medicine · 2026Review
- Genomic landscape of 340 virulent Acinetobacter bacteriophages reveals anti-CRISPR-enriched candidates for therapeutic prioritization.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Harnessing phage-ciprofloxacin synergy to overcome multidrug-resistant infections and biofilm persistence.Archives of microbiology · 2026Article
- Emerging therapies and diagnostic innovations for multidrug-resistant infections in kidney allograft recipients: Challenges and future directions.World journal of nephrology · 2026Review
- Modeling Phage-Antibiotic Synergy, Innate Immunity, and Phage Resistance in Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2026Article
- Approaching the post-antibiotic era: phage therapy current practices and future horizons.mBio · 2026Review
- Article
- Bacterial Lysis Observation Over Time Assay (BLOTS) for High-Throughput Isolation, Sequencing, and Characterization of Bacteriophages.Current protocols · 2026Article
- First UK use of bacteriophage therapy with DAIR for chronicASM case reports · 2026Article
- Pharky, Phedro, Phractured, and StagePhright: complete genome sequences of four EK2 cluster Microbacterium phages.Microbiology resource announcements · 2026Article
- Review
- Discovery and biosynthesis of a novel diaminopropane-modified thymine in phage DNA.Nucleic acids research · 2026Article
- Bacteriophages AgainstViruses · 2026Review
- Phage Therapy Enhanced by Using Engineered Bacteriophages: A Powerful Antibacterial Tool to Address the Dilemma Posed by Multidrug-Resistant Bacterial Infections.International journal of molecular sciences · 2026Review
- Pharmacology of Bacteriophage Therapy in Children: A Re-Emerging Paradigm in Antibacterial Therapy.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Isolation and characterization of two phages infectingThe Journal of general virology · 2026Article
659 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
34 authors.
Robert T SchooleyDepartment of Medicine, University of California, San Diego, La Jolla, California, USA rschooley@ucsd.edu.
Biswajit BiswasBiological Defense Research Directorate, Naval Medical Research Center, Frederick, Maryland, USA.
Jason J GillDepartment of Animal Science, Texas A&M University, College Station, Texas, USA.
Adriana Hernandez-MoralesDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
Jacob LancasterCenter for Phage Technology, Texas A&M AgriLife Research and Texas A&M University, College Station, Texas, USA.
Lauren LessorCenter for Phage Technology, Texas A&M AgriLife Research and Texas A&M University, College Station, Texas, USA.
Jeremy J BarrDepartment of Biology, San Diego State University, San Diego, California, USA.
Sharon L ReedDepartment of Medicine, University of California, San Diego, La Jolla, California, USA.
Forest RohwerDepartment of Biology, San Diego State University, San Diego, California, USA.
Sean BenlerDepartment of Biology, San Diego State University, San Diego, California, USA.
Anca M SegallDepartment of Biology, San Diego State University, San Diego, California, USA.
Randy TaplitzDepartment of Medicine, University of California, San Diego, La Jolla, California, USA.
Davey M SmithDepartment of Medicine, University of California, San Diego, La Jolla, California, USA.
Kim KerrDepartment of Medicine, University of California, San Diego, La Jolla, California, USA.
Monika KumaraswamyDepartment of Medicine, University of California, San Diego, La Jolla, California, USA.
Victor NizetDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.
Leo LinDepartment of Pediatrics, University of California, San Diego, La Jolla, California, USA.
Melanie D McCauleyDepartment of Medicine, University of California, San Diego, La Jolla, California, USA.
Steffanie A StrathdeeDepartment of Medicine, University of California, San Diego, La Jolla, California, USA.
Constance A BensonDepartment of Medicine, University of California, San Diego, La Jolla, California, USA.
Robert K PopeNational Biodefense Analysis and Countermeasures Center, Frederick, Maryland, USA.
Brian M LerouxNational Biodefense Analysis and Countermeasures Center, Frederick, Maryland, USA.
Andrew C PicelDepartment of Radiology, University of California, San Diego, La Jolla, California, USA.
Alfred J MateczunBiological Defense Research Directorate, Naval Medical Research Center, Frederick, Maryland, USA.
Katherine E CilwaAdvanced Surgical Imaging Program, Department of Regenerative Medicine, Naval Medical Research Center, Silver Spring, Maryland, USA.
James M RegeimbalBiological Defense Research Directorate, Naval Medical Research Center, Frederick, Maryland, USA.
Luis A EstrellaBiological Defense Research Directorate, Naval Medical Research Center, Frederick, Maryland, USA.
David M WolfeBiological Defense Research Directorate, Naval Medical Research Center, Frederick, Maryland, USA.
Matthew S HenryBiological Defense Research Directorate, Naval Medical Research Center, Frederick, Maryland, USA.
Javier QuinonesBiological Defense Research Directorate, Naval Medical Research Center, Frederick, Maryland, USA.
Scott SalkaAmpliPhi Biosciences, San Diego, California, USA.
Kimberly A Bishop-LillyBiological Defense Research Directorate, Naval Medical Research Center, Frederick, Maryland, USA.
Ry YoungCenter for Phage Technology, Texas A&M AgriLife Research and Texas A&M University, College Station, Texas, USA.
Theron HamiltonBiological Defense Research Directorate, Naval Medical Research Center, Frederick, Maryland, USA.
Funding
RESEARCH IN INFECTIOUS DISEASEST32AI007036 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NIZET, VICTOR · 1985 to 2025
$9.2MCONTROL OF VIRUS-INDUCED LYSISR01GM027099 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI YOUNG, RYLAND FLETCHER · 1985 to 2019
$4.6MNIAID NIH HHS T32 AI007036NIGMS NIH HHS R01 GM027099
Abstract
Widespread antibiotic use in clinical medicine and the livestock industry has contributed to the global spread of multidrug-resistant (MDR) bacterial pathogens, including
Indexed as
Acinetobacter baumanniiAcinetobacter InfectionsAgedAnti-Bacterial AgentsBacteriophagesDrug Resistance, Multiple, BacterialGallstonesHumansMaleMinocyclinePancreatic PseudocystPancreatitis, Acute NecrotizingPhage TherapyAnti-Bacterial AgentsMinocyclineAcinetobacterbacteriophage therapymultidrug resistance
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT07275905ClinicalTrials.gov
NCT07619924ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.