Evidence map›Paper›PMID 28807907›Full record

ArticleAntimicrobial agents and chemotherapy2017

Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response.

Marianne Lucas-Hourani, Daniel Dauzonne, Hélène Munier-Lehmann, Samira Khiar, Sébastien Nisole, Julien Dairou, Olivier Helynck, Philippe V Afonso, Frédéric Tangy, Pierre-Olivier Vidalain

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Unlocking STING as a Therapeutic Antiviral Strategy.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Article
  8. A Bioluminescent 3CLViruses · 2021
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Marianne Lucas-HouraniUnité de Génomique Virale et Vaccination, Institut Pasteur, CNRS UMR3569, Paris, France.
Daniel DauzonneInstitut Curie, Centre de Recherche, CNRS UMR3666, INSERM U1143, Paris, France.
Hélène Munier-LehmannUnité de Chimie et Biocatalyse, Institut Pasteur, CNRS UMR3523 Paris, France.
Samira KhiarUnité de Génomique Virale et Vaccination, Institut Pasteur, CNRS UMR3569, Paris, France.
Sébastien NisoleIRIM CNRS UMR9004, Université de Montpellier, Montpellier, France.
Julien DairouEquipe Chimie Bio-inorganique des Dérivés Soufrés et Pharmacochimie, Université Paris Descartes, CNRS UMR8601, Paris, France.
Olivier HelynckUnité de Chimie et Biocatalyse, Institut Pasteur, CNRS UMR3523 Paris, France.
Philippe V AfonsoUnité d'Epidémiologie et Physiopathologie des Virus Oncogènes, Département de Virologie, Institut Pasteur, CNRS UMR3569, Paris, France.
Frédéric TangyUnité de Génomique Virale et Vaccination, Institut Pasteur, CNRS UMR3569, Paris, France ftangy@pasteur.fr pierre-olivier.vidalain@parisdescartes.fr.
Pierre-Olivier VidalainUnité de Génomique Virale et Vaccination, Institut Pasteur, CNRS UMR3569, Paris, France ftangy@pasteur.fr pierre-olivier.vidalain@parisdescartes.fr.
Institut Pasteur · FRCentre National de la Recherche Scientifique · FRUniversité Paris Cité · FRInstitut Curie · FRUniversité de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antiviral AgentsCell LineChikungunya virusChromonesDicumarolDihydroorotate DehydrogenaseEnzyme InhibitorsHEK293 CellsHumansImmunity, InnateIndolesInterferon LambdaInterferonsInterferon Type IMeasles virusOxidoreductases Acting on CH-CH Group Donors3-(1H-indol-3-yl)-2,3-dihydro-4H-furo(3,2-c)chromen-4-oneAntiviral AgentsChromonesDicumarolDihydroorotate DehydrogenaseEnzyme InhibitorsIndolesInterferon LambdaInterferonsInterferon Type IOxidoreductases Acting on CH-CH Group DonorsPyrimidinesantiviral agentsinnate immunityinterferonspyrimidine metabolism

Identifiers

PMID28807907
PMCPMC5610480
OpenAlexW2750491563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.