Evidence map›Paper›PMID 28807902›Full record

ArticleDevelopment (Cambridge, England)2017

H2Av facilitates H3S10 phosphorylation but is not required for heat shock-induced chromatin decondensation or transcriptional elongation.

Yeran Li, Chao Wang, Weili Cai, Saheli Sengupta, Michael Zavortink, Huai Deng, Jack Girton, Jørgen Johansen, Kristen M Johansen

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yeran LiRoy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.
Chao WangRoy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.ORCID 0000-0001-8089-8786
Weili CaiRoy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.ORCID 0000-0002-6781-5322
Saheli SenguptaRoy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.
Michael ZavortinkRoy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.
Huai DengRoy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.
Jack GirtonRoy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.
Jørgen JohansenRoy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA jorgen@iastate.edu kristen@iastate.edu.ORCID 0000-0002-8662-3449
Kristen M JohansenRoy J. Carver Department of Biochemistry, Biophysics, and Molecular Biology, Iowa State University, Ames, Iowa 50011, USA jorgen@iastate.edu kristen@iastate.edu.ORCID 0000-0003-1082-0873
Iowa State University · US

Funding

Regulation of Chromatin Structure byPhosphorylationR01GM062916 · NIGMS · IOWA STATE UNIVERSITY · PI JOHANSEN, JORGEN, JOHANSEN, KRISTEN M · 2001 to 2014
$3.5M
NIGMS NIH HHS R01 GM062916
6 · The paper itself

Abstract

A model has been proposed in which JIL-1 kinase-mediated H3S10 and H2Av phosphorylation is required for transcriptional elongation and heat shock-induced chromatin decondensation. However, here we show that although H3S10 phosphorylation is indeed compromised in the

Indexed as

Transcription Elongation, GeneticAnimalsChromatinDrosophila melanogasterDrosophila ProteinsEuchromatinGreen Fluorescent ProteinsHeat-Shock ResponseHistonesImmunoblottingImmunohistochemistryLac OperonMutationPhosphorylationPhosphoserinePoly(ADP-ribose) PolymerasesChromatinDrosophila ProteinsEuchromatinGreen Fluorescent ProteinsHis2Av protein, DrosophilaHistonesJIL-1 protein, DrosophilaPhosphoserinePoly(ADP-ribose) PolymerasesProtein Serine-Threonine KinasesChromatin structureDrosophilaH2AvHis2AvHistone H3S10 phosphorylationJIL-1 kinase

Identifiers

PMID28807902
PMCPMC5612252
OpenAlexW2749849220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.