Evidence map›Paper›PMID 28807897›Full record

ArticleDevelopment (Cambridge, England)2017

Cytoplasmic poly (A)-binding protein critically regulates epidermal maintenance and turnover in the planarian

Dhiru Bansal, Jahnavi Kulkarni, Kavana Nadahalli, Vairavan Lakshmanan, Srikar Krishna, Vidyanand Sasidharan, Jini Geo, Shilpa Dilipkumar, Renu Pasricha, Akash Gulyani and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. An insight into planarian regeneration.Cell proliferation · 2022
    Review
  7. Article
  8. Collagen IV differentially regulates planarian stem cell potency and lineage progression.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Dhiru BansalInstitute for Stem Cell Biology and Regenerative Medicine, GKVK PO, Bellary Road, Bangalore 560065, India.
Jahnavi KulkarniInstitute for Stem Cell Biology and Regenerative Medicine, GKVK PO, Bellary Road, Bangalore 560065, India.
Kavana NadahalliInstitute for Stem Cell Biology and Regenerative Medicine, GKVK PO, Bellary Road, Bangalore 560065, India.
Vairavan LakshmananInstitute for Stem Cell Biology and Regenerative Medicine, GKVK PO, Bellary Road, Bangalore 560065, India.
Srikar KrishnaInstitute for Stem Cell Biology and Regenerative Medicine, GKVK PO, Bellary Road, Bangalore 560065, India.
Vidyanand SasidharanInstitute for Stem Cell Biology and Regenerative Medicine, GKVK PO, Bellary Road, Bangalore 560065, India.
Jini GeoNational Centre for Biological Sciences, GKVK PO, Bellary Road, Bangalore 560065, India.ORCID 0000-0002-1119-0829
Shilpa DilipkumarInstitute for Stem Cell Biology and Regenerative Medicine, GKVK PO, Bellary Road, Bangalore 560065, India.
Renu PasrichaNational Centre for Biological Sciences, GKVK PO, Bellary Road, Bangalore 560065, India.ORCID 0000-0002-9659-1225
Akash GulyaniInstitute for Stem Cell Biology and Regenerative Medicine, GKVK PO, Bellary Road, Bangalore 560065, India.
Srikala RaghavanInstitute for Stem Cell Biology and Regenerative Medicine, GKVK PO, Bellary Road, Bangalore 560065, India.
Dasaradhi PalakodetiInstitute for Stem Cell Biology and Regenerative Medicine, GKVK PO, Bellary Road, Bangalore 560065, India dasaradhip@instem.res.in palakodeti76@gmail.com.ORCID 0000-0003-2219-4785
Institute for Stem Cell Biology and Regenerative Medicine · INManipal Academy of Higher Education · INNational Centre for Biological Sciences · IN

Funding

Wellcome Trust
6 · The paper itself

Abstract

Identifying key cellular events that facilitate stem cell function and tissue organization is crucial for understanding the process of regeneration. Planarians are powerful model system to study regeneration and stem cell (neoblast) function. Here, using planaria, we show that the initial events of regeneration, such as epithelialization and epidermal organization are critically regulated by a novel cytoplasmic poly A-binding protein, SMED-PABPC2. Knockdown

Indexed as

AnimalsCell LineageCell ProliferationCytoplasmEpidermisEpitheliumExtracellular MatrixGene Knockdown TechniquesHomeostasisModels, BiologicalPlanariansPoly(A)-Binding Protein IRegenerationRNA, MessengerWound HealingPoly(A)-Binding Protein IRNA, MessengerEpidermisNeoblastPlanariaPoly (A)-binding proteinsRegeneration

Identifiers

PMID28807897
PMCPMC5611960
OpenAlexW2750402818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.