Evidence map›Paper›PMID 28807693›Full record

ArticleArchives of physical medicine and rehabilitation2018

Safety and Feasibility of Rehabilitation Interventions in Children Undergoing Hematopoietic Stem Cell Transplant With Thrombocytopenia.

Katarzyna Ibanez, Noel Espiritu, Regine L Souverain, Laura Stimler, Lauren Ward, Elyn R Riedel, Rachel Lehrman, Farid Boulad, Michael Dean Stubblefield

Abstract read
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 18 citations in OpenAlex.

  1. Haematopoietic stem cell transplantation for children and young people: is there a role for prehabilitation? A scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Katarzyna IbanezDepartment of Neurology, Rehabilitation Medicine Service, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: ibanezk@mskcc.org.
Noel EspirituDepartment of Neurology, Rehabilitation Medicine Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Regine L SouverainDepartment of Neurology, Rehabilitation Medicine Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Laura StimlerAuerbach School of Occupational Therapy, Spalding University, Louisville, KY.
Lauren WardDepartment of Neurology, Rehabilitation Medicine Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Elyn R RiedelDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Rachel LehrmanDepartment of Pediatrics, Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Farid BouladDepartment of Pediatrics, Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY.
Michael Dean StubblefieldSelect Medical, Kessler Institute for Rehabilitation, West Orange, NJ.
Memorial Sloan Kettering Cancer Center · USKessler Institute for Rehabilitation · USSpalding University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

objectiveTo analyze the relation between platelet counts, intensities of physical therapy (PT) and occupational therapy (OT) services received, and frequencies of bleeding complications in children undergoing hematopoietic stem cell transplant (HSCT) during a period of severe thrombocytopenia.

designRetrospective review study.

settingTertiary care hospital.

participantsChildren (N=63; age, <18y) hospitalized for HSCT in 2010 and 2011 who received PT and OT services while markedly thrombocytopenic (platelet count, ≤50K/mcL).

interventionsNot applicable.

main outcome measuresIntensities of PT and OT interventions, patients' platelet counts on specific therapy days, and any bleeding events (minor or major) that occurred during or shortly after rehabilitation interventions.

resultsSixty-two patients (accounting for 63 HSCTs) met the criteria for analysis. Fifty-six of these patients (57 HSCTs) underwent PT and/or OT while markedly thrombocytopenic. There was no correlation between platelet counts and intensities of rehabilitation interventions. There were no major bleeding events. There was no association between minor bleeding events and intensities of PT or OT interventions and no association between minor bleeding events and platelet counts. Only 5 minor bleeding events occurred during or after moderate or intensive therapy out of 346 PT and OT sessions (1.5%).

conclusionsThe results of our study suggest that bleeding complications during or after mobilization and supervised exercise during PT and OT in children with severe thrombocytopenia undergoing HSCT are minor and relatively rare. These are encouraging results for both patients and rehabilitation specialists treating this population who is at high risk of developing immobility-related complications.

Indexed as

Hematopoietic Stem Cell TransplantationPhysical Therapy ModalitiesActivities of Daily LivingAdolescentChildChild, PreschoolChildren with DisabilitiesFemaleHumansMalePlatelet CountRange of Motion, ArticularRetrospective StudiesThrombocytopeniaHematopoietic stem cell transplantationPediatricsRehabilitationThrombocytopenia

Identifiers

PMID28807693
PMCPMC6342002
OpenAlexW2742581379

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.