Evidence map›Paper›PMID 28807645›Full record

Trial reportThe Journal of urology2018

A Behavioral Weight Loss Program and Nonurinary Incontinence Lower Urinary Tract Symptoms in Overweight and Obese Women with Urinary Incontinence: A Secondary Data Analysis of PRIDE.

Benjamin N Breyer, Jennifer M Creasman, Holly E Richter, Deborah Myers, Kathryn L Burgio, Rena R Wing, Delia Smith West, John W Kusek, Leslee L Subak, PRIDE

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Bladder training for treating overactive bladder in adults.The Cochrane database of systematic reviews · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Benjamin N BreyerDepartments of Urology and Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, California; Department of Urology, University of California-San Francisco, San Francisco, California; Departments of Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, California. Electronic address: bbreyer@urology.ucsf.edu.
Jennifer M CreasmanDepartments of Obstetrics, Gynecology and Reproductive Sciences, Women's Health Clinical Research Center, University of California-San Francisco, San Francisco, California; Departments of Obstetrics, Gynecology and Reproductive Sciences, University of California-San Francisco, San Francisco, California.
Holly E RichterDepartment of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama.
Deborah MyersDepartments of Obstetrics and Gynecology, Warren Alpert Medical School at Brown University, Providence, Rhode Island.
Kathryn L BurgioDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama; Department of Veterans Affairs, Birmingham, Alabama.
Rena R WingMiriam Hospital, Providence, Rhode Island; Department of Psychiatry and Human Behavior, Warren Alpert Medical School at Brown University, Providence, Rhode Island.
Delia Smith WestDepartment of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina.
John W KusekNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
Leslee L SubakDepartment of Veterans Affairs, San Francisco, California.
PRIDE
Brown University · USUniversity of Alabama at Birmingham · USUniversity of California, San Francisco · USNational Institute of Diabetes and Digestive and Kidney Diseases · USSan Francisco VA Medical Center · USUniversity of South Carolina · US

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Weight Reduction for Incontinence Network(WIN)U01DK067860 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRADY, DEBORAH G · 2003 to 2007
$2.3M
Weight Reduction for Incontinence NetworkU01DK067861 · NIDDK · MIRIAM HOSPITAL · PI WING, RENA R · 2003 to 2007
$2.2M
Weight Reduction for Incontinence Network (WIN)U01DK067862 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FRANKLIN, FRANK A · 2003 to 2007
$1.7M
Patient Oriented Research and Mentoring in Obesity and Urinary IncontinenceK24DK080775 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SUBAK, LESLEE L · 2008 to 2019
$1.7M
NIDDK NIH HHS K24 DK080775NIDDK NIH HHS L30 DK092174NIDDK NIH HHS P30 DK079626NIDDK NIH HHS U01 DK067860NIDDK NIH HHS U01 DK067861NIDDK NIH HHS U01 DK067862
6 · The paper itself

Abstract

purposeWe sought to determine whether a behavioral weight reduction intervention would improve nonurinary incontinence lower urinary tract storage symptoms at 6 months, including urinary frequency, nocturia and urgency, compared to a structured education program serving as the control group among overweight and obese women with urinary incontinence. MATERIALS AND

methodsPRIDE (Program to Reduce Incontinence by Diet and Exercise) was a randomized clinical trial performed in 338 overweight or obese women with urinary incontinence. Participants were randomized, including 226 to 6-month behavioral weight loss intervention and 112 to the control group. All participants received a self-help behavioral treatment booklet to improve bladder control. On this secondary data analysis we examined changes in nonurinary incontinence lower urinary tract storage symptoms from baseline to 6 months and the impact of treatment allocation (intervention vs control), weight loss and physical activity.

resultsNonurinary incontinence lower urinary tract storage symptoms were common at baseline, varying from 48% to 62%. In the 2 groups combined women experienced significant improvement in nocturia, urgency and International Prostate Symptom Score at 6 months (all p <0.001). However, lower urinary tract storage symptom outcomes at 6 months did not differ between the intervention and control groups. Similarly no difference was observed in the amount of weight lost (5% or greater vs less than 5%) or physical activity (1,500 kcal or greater expenditure per week compared to less than 1,500 kcal).

conclusionsLower urinary tract storage symptoms were common among overweight and obese women with urinary incontinence. The prevalence decreased significantly after 6 months independent of treatment group assignment, amount of weight lost or physical activity. These improvements may have been due to self-help behavioral educational materials, trial participation or repeat assessment of symptoms.

Indexed as

AdultBehavior TherapyData AnalysisExerciseFemaleHumansMiddle AgedOverweightPatient Education as TopicPrevalenceTreatment OutcomeUrinary IncontinenceWeight LossWeight Reduction Programsfemalelower urinary tract symptomsobesityurination disordersweight loss

Identifiers

PMID28807645
PMCPMC6089611
OpenAlexW2744092149

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.