Evidence map›Paper›PMID 28807510›Full record

ReviewInternational journal of cardiology2017

Angina after percutaneous coronary intervention: The need for precision medicine.

Giampaolo Niccoli, Rocco Antonio Montone, Gaetano Antonio Lanza, Filippo Crea

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in International journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04661709 (Efficacy and Safety of Chinese Herbal Medicine Wen Xin Granules for the Treatment of Unstable Angina Pectoris With Yang Deficiency and Blood Stasis Syndrome), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04661709 phase4unknown statusstarted 2021, after this paper: background citation

Efficacy and Safety of Chinese Herbal Medicine Wen Xin Granules for the Treatment of Unstable Angina Pectoris With Yang Deficiency and Blood Stasis Syndrome: Study Protocol for a Randomized Controlled Trial

Ran2021Enrolled502Registered outcomes4Posted comparisons0ConditionsChinese Herbal Medicine, Coronary Heart Disease, Unstable AnginaArmsAspirin Enteric-coated Tablets, Atorvastatin calcium, Clopidogrel Hydrogen Sulfate 75 MG Oral Tablet, glyceryl trinitrate, Isosorbide Mononitrate Tab 20 MG
Open the trial in the graph
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Coronary Physiology: Delivering Precision Medicine?Reviews in cardiovascular medicine · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giampaolo NiccoliDepartment of Cardiovascular and Thoracic Sciences, Catholic University of the Sacred Heart, Rome, Italy. Electronic address: gniccoli73@hotmail.it.
Rocco Antonio MontoneDepartment of Cardiovascular and Thoracic Sciences, Catholic University of the Sacred Heart, Rome, Italy; Interventional Cardiology, IRCCS Policlinico San Donato, Milan, Italy.
Gaetano Antonio LanzaDepartment of Cardiovascular and Thoracic Sciences, Catholic University of the Sacred Heart, Rome, Italy.
Filippo CreaDepartment of Cardiovascular and Thoracic Sciences, Catholic University of the Sacred Heart, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistence or recurrence of angina after successful percutaneous coronary intervention (PCI) represent an important clinical issue involving from one fifth to one third of patients undergoing myocardial revascularization at one-year follow-up. A systematic approach to this syndrome is strongly needed. Precision medicine is particularly important in addressing angina after successful PCI because of the multiple underlying causes. Restenosis or coronary atherosclerosis progression explain symptom recurrence after successful PCI in some patients, while functional causes, including vasomotor abnormalities of epicardial coronary arteries and/or coronary microvascular dysfunction, explain symptoms in the remaining patients. In this review, we summarize the mechanisms of persistent or recurrent angina after PCI, proposing a diagnostic algorithm and a systematic therapeutic approach.

Indexed as

Angina PectorisHumansPercutaneous Coronary InterventionPostoperative ComplicationsPrecision MedicineRandomized Controlled Trials as TopicTreatment OutcomeAnginaMicrovascular dysfunctionPercutaneous coronary intervention

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.